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Letter
Nature Genetics 31, 400–404 (1 August 2002) | doi:10.1038/ng929
Systematic screen for human disease genes in yeast
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Abstract
High similarity between yeast and human mitochondria allows functional genomic study of Saccharomyces cerevisiae to be used to identify human genes involved in disease. So far, 102 heritable disorders have been attributed to defects in a quarter of the known nuclear-encoded mitochondrial proteins in humans.
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