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Research
Nature Biotechnology 22, 1423–1428 (1 December 2004) | doi:10.1038/nbt1023
Antidote-mediated control of an anticoagulant aptamer in vivo
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Abstract
Patient safety and treatment outcome could be improved if physicians could rapidly control the activity of therapeutic agents in their patients. Antidote control is the safest way to regulate drug activity, because unlike rapidly clearing drugs, control of the drug activity is independent of underlying patient physiology and co-morbidities.
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