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Nature 427, 75-78 (1 January 2004) | doi:10.1038/nature02170;
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Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation
The RGS proteins are GTPase activating proteins that accelerate the deactivation of G proteins in a variety of signalling pathways in eukaryotes. RGS9 deactivates the G proteins (transducins) in the rod and cone phototransduction cascades.
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