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Nature 426, 570-574 (4 December 2003) | doi:10.1038/nature02166;
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Proteomic characterization of the human centrosome by protein correlation profiling
The centrosome is the major microtubule-organizing centre of animal cells and through its influence on the cytoskeleton is involved in cell shape, polarity and motility. It also has a crucial function in cell division because it determines the poles of the mitotic spindle that segregates duplicated chromosomes between dividing cells.
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