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Nature 422, 633-637 (10 April 2003) | doi:10.1038/nature01546;
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Noise in eukaryotic gene expression
Transcription in eukaryotic cells has been described as quantal, with pulses of messenger RNA produced in a probabilistic manner. This description reflects the inherently stochastic nature of gene expression, known to be a major factor in the heterogeneous response of individual cells within a clonal population to an inducing stimulus.
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