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Nature 418, 344-348 (18 July 2002) | doi:10.1038/nature00829;
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Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
Calorie restriction (CR) extends lifespan in a wide spectrum of organisms and is the only regimen known to lengthen the lifespan of mammals. We established a model of CR in budding yeast Saccharomyces cerevisiae.
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