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Nature 415, 526-530 (16 January 2002) | doi:10.1038/nature711;

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Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1

Neurofibromatosis type I (NF1) is one of the most common single-gene disorders that causes learning deficits in humans. Mice carrying a heterozygous null mutation of the Nf1 gene (Nf1+/|[minus]|) show important features of the learning deficits associated with NF1 (ref.

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