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Nature 401, 547-548 (7 October 1999) | doi:10.1038/44062;
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Cell division: A histone-H3-like protein in C. elegans
The segregation of a chromosome during mitosis is mediated by a region of the chromosome known as the centromere, which organizes the kinetochore, to which the spindle microtubules attach. Many organisms have monocentric chromosomes, in which the centromeres map to single loci, whereas others, including the nematode Caenorhabditis elegans, have holocentric chromosomes, in which non-localized kinetochores extend along the length of each chromosome.
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