TABLE 1
FROM:
The effect of a rapid weight loss on lipid profile and glycemic control in obese type 2 diabetic patients
H Harder, B Dinesen and A Astrup
BACK TO ARTICLETable 1. Clinical characteristics, plasma parameters, and lipid profile of the subjects (n=10) at baseline and after 8-week LCD
| Variable | 0 weeks | 8 weeks | P-value |
|---|---|---|---|
| Body weight (kg) | 100.6 4.7 | 89.3 4.3 | <0.001 |
| Waist circumference (cm) | 110.9 2.6 | 101.0 2.8 | <0.001 |
| Fasting blood glucose (mmol/l) | 8.1 0.7 | 6.4 0.4 | 0.050 |
| Hemoglobin A1c (HbA1c (%)) | 7.0 0.1 | 6.1 0.1 | 0.006 |
| Insulin (pmol/l) | 176.1 43.0 | 85.5 19.2 | 0.034 |
| S-alanine aminotransferase (U/l) | 32.5 2.6 | 39.7 3.7 | 0.073 |
| S-aspartate aminotransferase (U/l) | 25.6 2.5 | 28.1 3.1 | 0.159 |
| Systolic blood pressure (mmHg) | 155 5 | 149 7 | 0.326 |
| Diastolic blood pressure (mmHg) | 80 3 | 85 4 | 0.096 |
| Triglyceride (mmol/l) | 2.18 0.26 | 1.34 0.26 | 0.003 |
| Total cholesterol (mmol/l) | 5.65 0.28 | 4.51 0.28 | <0.001 |
| LDL cholesterol (mmol/l) | 3.84 0.26 | 3.17 0.24 | 0.012 |
| HDL cholesterol (mmol/l) | 1.12 0.07 | 1.06 0.04 | 0.288 |
| LDL 1 (mmol/l) | 0.82 0.34 | 1.43 0.29 | 0.169 |
| LDL 2 (mmol/l) | 2.22 0.40 | 1.52 0.29 | 0.170 |
| LDL 3 (mmol/l) | 0.67 0.40 | 0.12 0.07 | 0.221 |
| HDL 1 (mmol/l) | 0.48 0.06 | 0.49 0.04 | 0.787 |
| HDL 2 (mmol/l) | 0.07 0.02 | 0.11 0.02 | 0.147 |
| HDL 3 (mmol/l) | 0.58 0.02 | 0.46 0.03 | 0.008 |
| LDL size (nm) | 20.6 0.7 | 21.1 0.4 | 0.108 |
Values are given as average
s.e.m. FBG=fasting blood glucose. Before and after values within the group are compared with paired t-tests.
