Abstract
OBJECTIVE: To investigate whether oral factors stimulated by the presence of sucrose in the mouth are involved in the suppression of appetite following sucrose ingestion.
DESIGN: Ten male and 10 female healthy volunteers participated in four experimental conditions designed to provide differing levels of oro-sensory stimulation. Appetite and energy intake from a test meal were measured after subjects chewed and ingested sucrose-containing pastilles over a 10 min period, consumed a sucrose-containing jelly over a 5 min period, consumed a sucrose-containing drink within 2 min and drank plain water within 2 min. The three sucrose-containing preloads were similar in nutrient composition, each containing 251 kJ.
RESULTS: Ratings of hunger and fullness did not differ between the four conditions following ingestion of the preloads. However, energy intake from a test lunch was significantly reduced after consuming the pastilles when compared with the plain water and equicaloric sweet drink conditions.
CONCLUSION: These results suggest that enhanced oro-sensory stimulation from chewing the sweet food was involved in the suppression of food intake.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Lavin JH, French, SJ, Read, NW . Comparison of oral and gastric administration of sucrose and maltose on gastric emptying rate and appetite Int J Obes Relat Metab Disord 2002 26: 80–86.
Janowitz HD, Hollander F, Orringer D, Levy MH, Winkelstein, A, Kaufman, MR, Margolin SG . A quantitative study of the gastric secretory response to sham feeding in a human subject Gastroenterology 1950 16: 104–116.
Wolf S, Wolf HG . Human gastric function Oxford University Press: London 1947.
Cecil JE, Francis J, Read NW . Relative contributions of intestinal, gastric, oro-sensory influences and information to changes in appetite induced by the same liquid meal Appetite 1998 31: 377–390.
Jordan HA . Voluntary intragastric feeding: oral and gastric contributions to food intake and hunger in man J Comp Physiol Psychol 1969 68: 498–506.
Novin D, Robinson K, Culbreth LA, Tordoff MG . Is there a role for the liver in the control of food intake Am J Clin Nutr 1985 42: 1050–1062.
De Graaf C, Hulshof T, Jas P . Short-term effects of different amounts of protein, fats and carbohydrates on satiety Am J Clin Nutr 1980 55: 33–38.
Poothullil JM . Oral satiation and the regulation of intake Physiol Behav 1995 57: 349–352.
Warwick ZS, Hall WG, Pappas TN, Schiffman SS . Taste and smell sensations enhance the satiating effect of both a high-carbohydrate and a high-fat meal in humans Physiol Behav 1993 53: 553–563.
Stunkard AJ, Messick S . The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger J Psychosom Res 1985 29: 71–83.
Dye L, Blundell JE . Menstrual cycle and appetite control: implications for weight regulation Hum Reprod 1997 12: 1142–1151.
Birch LL, McPhee L, Sullivan S . Children's food intake following drinks sweetened with sucrose or aspartame: time course effects Physiol Behav 1989 45: 387–395.
Booth DA, Campbell AT, Chase A . Temporal bounds of post-ingestive glucose induced satiety in man Nature 1979 228: 1104–1105.
Lavin JH, French SJ, Read NW . The effect of sucrose- and aspartame-sweetened drinks on energy intake, hunger and food choice of female, moderately restrained eaters Int J Obes Relat Metab Disord 1997 21: 37–42.
Rogers PJ, Carlyle J, Hill AJ, Blundell JE . Uncoupling sweet taste and calories: comparison of the effects of glucose and three high intensity sweeteners on hunger and food intake Physiol Behav 1988 43: 547–552.
DiMeglio DP, Mattes RD . Liquid versus solid carbohydrate: effect on food intake and body weight Int J Obes Relat Metab Disord 2000 24: 794–800.
Mattes RD . Dietary compensation by humans for supplemental energy provided as ethanol or carbohydrate in fluids Physiol Behav 1996 59: 179–187.
Geary N, Kissileff HR, Pi-Sunyer FX, Hinton V . Individual, but not simultaneous, glucagon and cholesystokinin infusions inhibit feeding in men Am J Physiol 1992 262: R975–R980.
Teff KL, Engelman K . Oral sensory stimulation improves glucose tolerance in humans: effects on insulin, C-peptide, and glucagon Am J Physiol 1996 270: R1371–R1379.
Teff KL, Levin BE, Engelman K . Oral sensory stimulation in men: effects on insulin, C-peptide, and catecholamines Am J Physiol 1993 265: R1223–R1230.
VanderWeele DA . Insulin is a prandial satiety hormone Physiol Behav 1994 56: 619–622.
Helman CA . Chewing gum is as effective as food in stimulating cephalic phase gastric secretion Am J Gastroenterol 1988 83: 640–642.
Richardson CT, Walsh JH, Cooper KA, Feldman M, Fordtran JS . Studies on the role of cephalic–vagal stimulation in the acid secretory response to eating in normal human subjects J Clin Invest 1977 60: 435–441.
Haber GB, Heaton K, Murphy D, Burroughs LF . Depletion and disruption of dietary fibre. Effects on satiety, plasma-glucose, and serum-insulin Lancet 1977 i: 679–682.
Tordoff MG, Alleva AM . Oral stimulation with aspartame increases hunger Physiol Behav 1990 47: 555–559.
Brala PM, Hagan RL . Effects of sweetness perception and caloric value of a preload on short term intake Physiol Behav 1983 30: 1–9.
Melanson KJ, Westerterp-Plantenga MS, Campfield LA, Saris WHM . Blood glucose and meal patterns in time-blinded males, after aspartame, carbohydrate, and fat consumption, in relation to sweetness perception Br J Nutr 1999 82: 437–446.
Castiglione KE, Read NW, French SJ . Food intake responses to upper gastrointestinal lipid infusions in humans Physiol Behav 1998 64: 141–145.
French SJ, Conlon CA, Mutuma ST, Arnold M, Read NW, Meijer G, Francis J . The effects of intestinal infusion of long-chain fatty acids on food intake in humans Gastroenterology 2000 119: 943–948.
de Graaf C, Schreurs A, Blauw YH . Short-term effects of different amounts of sweet and nonsweet carbohydrates on satiety and energy intake Physiol Behav 1993 54: 833–843.
Acknowledgements
This work was supported by a grant from The Sugar Bureau.
Author information
Authors and Affiliations
Corresponding author
Additional information
This paper relates to one previously published in IJO 26:1 (January 2002) on pages 80–86.
Rights and permissions
About this article
Cite this article
Lavin, J., French, S., Ruxton, C. et al. An investigation of the role of oro-sensory stimulation in sugar satiety?. Int J Obes 26, 384–388 (2002). https://doi.org/10.1038/sj.ijo.0801829
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.ijo.0801829
Keywords
This article is cited by
-
Homeostasis and food craving in obesity: a functional MRI study
International Journal of Obesity (2021)
-
Relationship between bite size per mouthful and dental arch size in healthy subjects
The Journal of Physiological Sciences (2019)
-
Short-term effects of a green coffee extract-, Garcinia c ambogia- and l-carnitine-containing chewing gum on snack intake and appetite regulation
European Journal of Nutrition (2018)
-
Effects of red pitaya juice supplementation on cardiovascular and hepatic changes in high-carbohydrate, high-fat diet-induced metabolic syndrome rats
BMC Complementary and Alternative Medicine (2014)
-
Effect of sugars in solutions on subjective appetite and short-term food intake in 9- to 14-year-old normal weight boys
European Journal of Clinical Nutrition (2014)