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| Paper |
| In-vivo quantitative hydrolipidic map of perirenal adipose tissue by chemical shift imaging at 4.7 Tesla |
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| E Lunati1,2, P Marzola1, E Nicolato1 and A Sbarbati1 |
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1Magnetic Resonance Laboratory, Institute of Human Anatomy and Histology, University of Verona, Verona, Italy
2INFM Unit, University of Pavia, Pavia, Italy
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Correspondence to: A Sbarbati, Institute of Anatomy and Histology, University of Verona, Medical Faculty, Strada Le Grazie 8, 37134, Verona, Italy. E-mail: SBARBATI@borgoroma.univr.it
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| Abstract |
| OBJECTIVE: In this work, chemical shift magnetic resonance imaging is used for in vivo quantitative evaluation of fat and water content in the perirenal white adipose tissue. DESIGN AND MEASUREMENTS: Experiments were carried out on female Sprague-Dawley rats with a 4.7 T magnet. Fat and water fractions were computed pixel-by-pixel from the chemical shift selective images with an algorithm of reconstruction that allowed parametric maps (called hydrolipidic maps) to be produced with a pixel size of 625´625 µm. RESULTS: Our findings indicate that, in the perirenal adipose tissue, the water content ranges between 15% and 20%, with slight differences between the ventral and dorsal portions, and between the left and right deposits. The mesenteric adipose tissue, observed for comparison, has a mean water content of 30%. CONCLUSION: The present work demonstrates that methods based on magnetic resonance imaging can be useful tools for non-invasive in vivo quantitative mapping of the hydrolipidic content of adipose tissues. International Journal of Obesity (2001) 25, 457-461 |
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| Keywords |
| MRI; fat; perirenal; map; rat |
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| April 2001, Volume 25, Number 4, Pages 457-461 |
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