Nature Publishing Group, publisher of Nature, and other science journals and reference works NATURE.COM NATURE NEWS NATUREJOBS NATUREEVENTS ABOUT NPG
Help Nature.com site index  
International Journal of Obesity
SEARCH     advanced search my account e-alerts subscribe register
Journal home
Advance online publication
Current issue
Archive
Press releases
For authors
For referees
Contact editorial office
About the journal
For librarians
Subscribe
Advertising
naturereprints
Contact NPG
Customer services
Site features
NPG Subject areas
Access material from all our publications in your subject area:
Biotechnology Biotechnology
Cancer Cancer
Chemistry Chemistry
Dentistry Dentistry
Development Development
Drug Discovery Drug Discovery
Earth Sciences Earth Sciences
Evolution & Ecology Evolution & Ecology
Genetics Genetics
Immunology Immunology
Materials Materials Science
Medical Research Medical Research
Microbiology Microbiology
Molecular Cell Biology Molecular Cell Biology
Neuroscience Neuroscience
Pharmacology Pharmacology
Physics Physics
Browse all publications
 
December 2000, Volume 24, Number 12, Pages 1707-1714
Table of contents    Previous  Abstract  Next   Full text  PDF
Paper
Rates of psychiatric disorders in a clinical study group of adolescents with extreme obesity and in obese adolescents ascertained viaa population based study
B Britz1, W Siegfried2, A Ziegler3, C Lamertz4, B M Herpertz-Dahlmann5, H Remschmidt1, H-U Wittchen4 and J Hebebrand1

1Clinical Research Group, Department of Child and Adolescent Psychiatry of the University of Marburg, Marburg, Germany

2Obesity Treatment Center Berchtesgaden, Germany

3Institute of Medical Biometry and Epidemiology of the University of Marburg, Marburg, Germany

4Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology Unit, Munich, Germany

5Department of Child and Adolescent Psychiatry of the Technical University of Aachen, Aachen, Germany

Correspondence to: J Hebebrand, Clinical Research Group, Department of Child and Adolescent Psychiatry of the University of Marburg, Hans-Sachs-Str. 6, D-35033 Marburg, Germany.Hebebran@post.med.uni-marburg.de

Abstract

OBJECTIVE: To compare rates of DSM-IV psychiatric disorders between (1) a clinical study group of extremely obese adolescents and young adults, (2) gender-matched population-based obese controls and (3) a population-based control group of the same age range.

DESIGN: Rates of psychiatric disorders were assessed in (1) the clinical study group of obese adolescents and (2) the population based sample of obese adolescents, and compared to (3) a large population-based control group using a standardized psychiatric interview.

SUBJECTS: (1) Clinical study group: 30 female and 17 male extremely obese adolescents and young adults (age range: 15-21 y; mean BMI:42.4 kg/m2). (2) Thirty females and 17 males with the highest BMI (age range 15-21 y; mean BMI:29.8 kg/m2) of a population-based control group encompassing 1655 (805 males) adolescents and young adults. (3) The population based control group excluding the 30 females and 17 males with the highest BMI (n=1608; 788 males).

MEASUREMENTS: Munich-Composite International Diagnostic Interview (M-CIDI) allowing for DSM-IV diagnoses.

RESULTS: High rates of mood, anxiety, somatoform and eating disorders were detected in the clinical sample of obese adolescents which exceeded those observed in population controls (all P-values<0.01). Rates between population-based obese adolescents and young adults and population controls did not differ. In most patients the psychiatric disorders set in after onset of obesity. 57% and 35% of the female and male patients, respectively, reported eating binges with lack of control. However, less than one-half of these patients qualified for a DSM-IV diagnosis of an eating disorder.

CONCLUSIONS: Extremely obese adolescents and young adults who seek long-term inpatient treatment have a high lifetime prevalence for affective, anxiety, somatoform and eating disorders. Because the mean BMI of the clinical study group was considerably higher than that of the obese population controls, we were not able to clarify whether the high rate of psychopathology in the study group was related to the extreme obesity or to their treatment-seeking behavior.

International Journal of Obesity (2000) 24, 1707-1714

Keywords

binge eating; eating disorders; mood disorders; anxiety disorders; somatoform disorders; bulimia nervosa

Received 12 November 1999; revised 24 May 2000; accepted 7 July 2000
December 2000, Volume 24, Number 12, Pages 1707-1714
Table of contents    Previous  Abstract  Next   Full text  PDF
Privacy Policy © 2000 Nature Publishing Group