International Journal of Obesity
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November 2000, Volume 24, Number 11, Pages 1453-1458
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Paper
Waist circumference and waist-to-height ratio are better predictors of cardiovascular disease risk factors in children than body mass index
S C Savva1, M Tornaritis1, M E Savva1, Y Kourides1, A Panagi1, N Silikiotou1, C Georgiou1 and A Kafatos2

1Research and Education Program of Child Health, Cyprus

2Department of Social and Preventive Medicine, University of Crete School of Medicine, Crete, Greece

Correspondence to: S C Savva, Research and Education Program of Child Health, 138 Limassol Ave, Flat 205, Nicosia 2015, Cyprus.samar1@cytanet.com.cy

Abstract

BACKGROUND: Visceral adipose tissue is associated with increased risk for cardiovascular disease risk factors and morbidity from cardiovascular diseases. Waist measurement and waist-to-height ratio (WHtR) have been used as proxy measures of visceral adipose tissue, mainly in adults.

OBJECTIVE: To validate body mass index (BMI), waist circumference and WHtR as predictors for the presence of cardiovascular disease risk factors in children of Greek-Cypriot origin.

SUBJECTS AND METHODS: A total of 1037 boys and 950 girls with mean age 11.4±0.4 y were evaluated. Dependent variables for the study were total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholestrol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and systolic (SBP) and diastolic (DBP) blood pressure.

RESULTS: When children were divided into two groups according to the 75th percentile for BMI, waist circumference and WHtR, all dependent variables had higher mean values in the highest percentile groups in WHtR groups and almost all variables in BMI and waist circumference groups. Adjusted odds ratios for predicting pathological values of cardiovascular disease risk factors were slightly higher for the highest WHtR group for predicting lipid and lipoprotein pathological values and for the highest BMI groups in predicting high blood pressure measurement. Using stepwise multiple regression analysis to explain the variance of the dependent variables, waist circumference was the most significant predictor for all variables both for boys and girls, whereas BMI had the lowest predictive value for the detection of cardiovascular disease risk factors.

CONCLUSION: Waist circumference and WHtR are better predictors of cardiovascular disease risk factors in children than BMI. Further studies are necessary to determine the cutoff points for these indices for an accurate prediction of risk factors.

International Journal of Obesity (2000) 24, 1453-1458

Keywords

cardiovascular; BMI; waist; waist-to-height ratio; children

Received 31 August 1999; revised 22 May 2000; accepted 22 May 2000
November 2000, Volume 24, Number 11, Pages 1453-1458
Table of contents    Previous  Abstract  Next   Full text  PDF