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October 1997, Volume 21, Number 10, Pages 948-951
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Paper
Association of intraabdominal fat and carotid atherosclerosis in non-obese middle-aged men with normal glucose tolerance
M Yamamoto1, G Egusa1, H Hara2 and M Yamakido1

1Second Department of Internal Medicine, Hiroshima University School of Medicine, Hiroshima and

2Nippon Telegraph and telephone corporation, NTT Hiroshima Health Administration Center, Hiroshima, Japan

Correspondence: Dr Maki Yamamoto, Second Department of Internal Medicine, Hiroshima University School of Medicine, 1-2-3 Kasumi, Minami-ku, Hiroshima 734, Japan.

Abstract

OBJECTIVE: To investigate the association of visceral fat accumulation and carotid atherosclerosis in non-obese men with normal glucose tolerance. SUBJECTS: Ninety eight middle-aged men with normal glucose tolerance who had a body mass index (BMI)<25 kg/m2 (mean age: 52.6 y, mean BMI: 22.5 kg/m2). METHOD: Using ultrasonography, we simultaneously measured the abdominal fat distribution and intima-media thickness (IMT) of the carotid artery wall. RESULTS: Pmax, an index of the absolute amount of visceral fat, was found to be significantly correlated with IMT and fasting insulin concentration (r=0.37, P<0.005 and r=0.54, P<0.0001). Abdominal wall fat index (AFI), the ratio of maximum thickness of the preperitoneal fat and the minimum thickness of the subcutaneous fat, was not correlated with IMT. CONCLUSION: Visceral fat accumulation may play a role in the progression of atherosclerosis even in non-obese middle-aged men.

Keywords

ultrasound; fat distribution; visceral fat; carotid atherosclerosis

Received March 1997; revised June 1997; accepted 20 June 1997
October 1997, Volume 21, Number 10, Pages 948-951
Table of contents    Previous  Abstract  Next   Article  PDF
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