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| October 1997, Volume 21, Number 10, Pages 897-902 |
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| Paper |
| Insulinaemia and slight overweight: the case of Vietnamese hypertensives |
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| H Van Minh1, Le Chi Thanh1, BN Phan Thi1, Tran do Trinh2, Tran Duc Tho2 and P Valensi3 |
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1Hue Medical School, Hue, Vietnam
2Bach Mai Hospital, Hanoi, Vietnam
3Jean Verdier Hospital, Laboratory of Nutrition and Metabolic Diseases, Paris-Nord University, Bondy, France
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Correspondence: Professor Paul Valensi, Hôpital Jean Verdier, Service d'Endocrinologie Diabétologie Nutrition, avenue du 14 Juillet, 93143 Bondy Cedex France |
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| Abstract |
| OBJECTIVE: To examine the relationship between hypertension, overweight and indices of insulin resistance in Vietnamese subjects. PATIENTS: One hundred and eight hypertensive subjects (51 men and 57 women) over 40 y of age were compared with 36 control subjects over 40 y of age. METHODS: Blood glucose and plasma insulin were measured at fasting and 2 h after 75 g glucose taken orally. RESULTS: Hypertensive subjects had significantly higher body mass index (BMI), triceps skinfold, waist and hip circumferences and waist/hip ratio. Glycaemia at fasting and after glucose were similar in the two groups. Insulinaemia at fasting and after glucose were significantly higher in the hypertensive subjects. In the whole series of hypertensive subjects, plasma insulin and insulin/glucose ratio at fasting and after glucose correlated significantly with BMI, triceps skinfold and waist and hip circumferences. After exclusion of the subjects with BMI>22 kg/m2, compared with the controls, plasma insulin and insulin/glucose ratio were significantly higher in the whole hypertensive group and separately in hypertensive men and women. The logistic regression analyses have shown that plasma insulin and insulin/glucose ratio at fasting and after glucose were significantly associated with hypertension, independently of gender, BMI and waist circumference. CONCLUSION: This study shows that in Vietnamese people, essential hypertension is associated with a significant increase in BMI, which however remains far lower than the definition threshold of occidental obesity and with a state of insulin resistance found despite very slight or no excess weight. |
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| Keywords |
| insulin resistance; hypertension; anthropometry; overweight |
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| Received January 1997; revised 27 May 1997; accepted 29 May 1997 |
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| October 1997, Volume 21, Number 10, Pages 897-902 |
| Table of contents Previous Abstract Next Article PDF |
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