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Preputial graft in penile curvature correction: preliminary results

Abstract

Our purpose is to assess efficacy and complications of preputial skin graft for treatment of penile curvatures by grafting corporoplasty. Five congenital curvature and 14 Peyronie's disease patients were treated by grafting corporoplasty using preputial skin. Patients were evaluated by medical history and International Index of Erectile Function-5 (IIEF-5) questionnaire. After injection-induced erection, patients were evaluated by penile length measurement and color Duplex. Patients were re-evaluated 1 month later and advised to start intercourse. Patients were also evaluated during the 3rd and 12th months postoperatively, as per the original protocol. By the end of the follow-up period, 75% of patients were satisfied with straightened penises, without dilatation of the graft (ballooning) or venous leakage. Patients also exhibited a mean increase of two units in IIEF-5 score. Penile straightening and satisfaction rate were lower in the remaining 25% of patients, but no complaints of worsening erection or bulging of the graft area were reported. Preputial graft is an inexpensive procedure involving a tissue familiar to the urologist. The results of grafting corporoplasty are promising, without significant complications.

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References

  1. Ralph D . For the motion: surgery is the best choice for Peyronie's disease. Eur Urol 2006; 49: 1127–1129.

    Article  PubMed  Google Scholar 

  2. Montorsi F, Guazzoni G, Barbieri L, Maga T, Rigatti P, Graziottin A et al. AMS 700 CX inflatable penile implants for Peyronie's disease: functional results, morbidity and patient–partner satisfaction. Int J Impot Res 1996; 8: 81–86.

    CAS  PubMed  Google Scholar 

  3. Andrews HO, Al-Akraa M, Pryor JP, Ralph DJ . The Nesbit operation for Peyronie's disease: an analysis of the failures. BJU Int 2001; 87: 658–660.

    Article  CAS  PubMed  Google Scholar 

  4. Montorsi F, Salonia A, Maga T, Bua L, Guazzoni G, Barbieri L et al. Evidenced based assessment of long-term results of plaque incision and vein grafting for Peyronie's disease. J Urol 2000; 163: 1704–1708.

    Article  CAS  PubMed  Google Scholar 

  5. Kadioglu A, Akman T, Sanli O, Gurkan L, Cakan M, Celtik M . Surgical treatment of Peyronie's disease: a critical analysis. Eur Urol 2006; 50: 235–248.

    Article  PubMed  Google Scholar 

  6. Oates CP, Pickard RS, Powell PH, Murthy LN, Whittingham TA . The use of duplex ultrasound in the assessment of arterial supply to the penis in vasculogenic impotence. J Urol 1995; 153: 354–357.

    Article  CAS  PubMed  Google Scholar 

  7. Fürst G, Müller-Mattheis V, Cohnen M, Trautner C, Haastert B, Saleh A et al. Venous incompetence in erectile dysfunction: evaluation with color-coded duplex sonography and cavernosometry/-graphy. Eur Radiol 1999; 9: 35–41.

    Article  PubMed  Google Scholar 

  8. Lue TF, El-Sakka Al . Venous patch graft for Peyronie's disease: I. Technique. J Urol 1998; 160: 2047–2049.

    Article  CAS  PubMed  Google Scholar 

  9. Kadioglu A, Sanli O, Akman T, Cakan M, Erol B, Mammadov F . Surgical treatment of Peyronie's disease: a single center experience with 145 patients. Eur Urol 2008; 53: 432–439.

    Article  PubMed  Google Scholar 

  10. Ralph DJ . Editorial comment on: surgical treatment of Peyronie's disease: a single center experience with 145 patients. Eur Urol 2008; 53: 440.

    Article  PubMed  Google Scholar 

  11. Ralph DJ . The surgical treatment of Peyronie's disease. Eur Urol 2006; 50: 196–198.

    Article  PubMed  Google Scholar 

  12. Kadioglu A, Sanli O, Akman T, Ersay A, Guven S, Mammadov F . Graft materials in Peyronie's disease surgery: a comprehensive review. J Sex Med 2007; 4: 581–595.

    Article  PubMed  Google Scholar 

  13. Carson CC, Chun JL . Peyronie's disease: surgical management: autologous materials. Int J Impot Res 2002; 14: 329–335.

    Article  CAS  PubMed  Google Scholar 

  14. Austoni E, Colombo F, Mantovani F, Patelli E, Fenice O . Radical surgery and conservation of erection in Peyronie's disease. Arch Ital Urol Androl 1995; 67: 359–364.

    CAS  PubMed  Google Scholar 

  15. Barbagli G, Morgia G, Lazzeri M . Dorsal onlay skin graft bulbar urethroplasty: long-term follow-up. Eur Urol 2008; 53: 628–633.

    Article  PubMed  Google Scholar 

  16. Radopoulos D, Tzakas C, Dimitriadis G, Vakalopoulos I, Ioannidis S, Vasilakakis I . Dorsal on-lay preputial graft urethroplasty for anterior urethra strictures repair. Int Urol Nephrol 2007; 39: 497–503.

    Article  PubMed  Google Scholar 

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Correspondence to I Vakalopoulos.

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Radopoulos, D., Vakalopoulos, I. & Thanos, P. Preputial graft in penile curvature correction: preliminary results. Int J Impot Res 21, 82–87 (2009). https://doi.org/10.1038/ijir.2008.64

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