Case Report

International Journal of Impotence Research (2004) 16, 95–97. doi:10.1038/sj.ijir.3901154

Treatment of testosterone-induced gynecomastia with the aromatase inhibitor, anastrozole

E L Rhoden1,2 and A Morgentaler1

1Division of Urology, Beth Israel Deaconess Medical Center, Men's Health Boston, Harvard Medical School, Massachusetts, USA

Correspondence: EL Rhoden, Rua Jaragua 370/302, Bela Vista 90450-140, Porto Alegre, RS, Brazil. E-mail: ernanirhoden@yahoo.com.br; A Morgentaler, One Brookline Place, 624, Brookline, MA 02445, USA. E-mail: amorgent@caregroup.harvard.edu

2Supported by CAPES-Brazil (Government Foundation for Development of Postgraduation courses in Brazil).

Received 20 August 2003; Revised 2 October 2003; Accepted 14 October 2003.

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Abstract

Gynecomastia is an unusual side effect associated with testosterone replacement therapy (TRT) that has been traditionally treated with surgery, radiation, or discontinuation of testosterone supplementation. We report here our experience with two cases of gynecomastia in men undergoing TRT who were successfully treated with the aromatase inhibitor anastrozole.

Keywords:

anastrozole, hypogonadism, testosterone, risks, gynecomastia, aging male

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