Immunology and Cell Biology

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Three-dimensional structures of carbohydrate determinants of Lewis system antigens: Implications for effective antibody targeting of cancer

Elizabeth Yuriev, William Farrugia, Andrew M Scott and Paul A Ramsland

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Figure 1.

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Schematic representations of type 1 and 2 Lewis carbohydrate determinants. (a) Type 1 Leb tetrasaccharide determinant. (b) Type 2 Ley tetrasaccharide determinant. Note that the Lea (type 1) and Lex (type 2) epitopes are defined by core tripeptide structures that lack the alpha1-2 linked Fuc residues.

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