Brief Communication

Australian Journal of Experimental Biology and Medical Science (1971) 49, 309–312; doi:10.1038/icb.1971.32

VARIANTS IN HUMAN SERUM ALBUMIN AND CAERULOPLASMIN IN POPULATIONS FROM AUSTRALIA, NEW GUINEA, SOUTH AFRICA AND INDIA

EM McDermid1

1Department of Human Biology, John Curtin School of Medical Research, The Australian National University, P.O. Box 334, Canberra, A.C.T., 2601, Australia

Received 16 December 1970; Accepted 1 April 1971.

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Abstract

A survey of serum albumin and caeruloplasmin variants in populations of Australian Aborigines, Australian Caucasian, South African Bantu, Indians and New Cuinea indigenes has been carried out.

One serum albumin variant in 595 samples from New Cuinea was detected. The variant phenotype contained a band migrating more rapidly than normal phenotype but more slowly than the Albumin Naskapi. It is provisionally identified as Albumin New Cuinea in accordance with the usage of Weitkamp, Shreffler and Saave (1969). No serum albumin variants were found in the other populations sampled.

Caeruloplasmin variation was common amongst Bantu, rare amongst Aborigines and absent in Indians, Caucasians and New Guinea indigenes. The frequency of the CpA gene was 0dot035 in Bantu and 0dot002 in Aborigines.

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