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FEATURED OUTSTANDING OBSERVATIONS AND THEORETICAL ARTICLES
Spanning the breadth of immunology, Immunology & Cell Biology is proud to present Featured Outstanding Observations and Theoretical Articles - a collection of some of the top articles from recent years.
Outstanding Observations describe striking, reproducible observations that have extremely important conceptual implications but do not necessarily include insights into the underlying molecular mechanisms. Theoretical Articles are intended to challenge and provoke discussion in the international scientific community.
Theoretical Articles
Concepts for the development of a quantitative theory of clonal selection and class regulation using lessons from the original FREE
Philip D Hodgkin
Immunol Cell Biol 86: 161-165; advance online publication, January 22, 2008; doi:10.1038/sj.icb.7100164
Spatial modelling of brief and long interactions between T cells and dendritic cells FREE
Joost B Beltman, Athanasius F M Marée and Rob J de Boer
Immunol Cell Biol 85: 306-314; advance online publication, April 10, 2007; doi:10.1038/sj.icb.7100054
Abstract | Full Text | PDF (537K) | Supplementary information
Decision-making by the immune response FREE
Robin E Callard
Immunol Cell Biol 85: 300-305; advance online publication, May 1, 2007; doi:10.1038/sj.icb.7100060
Immunoepigenetics: the unseen side of cancer immunoediting FREE
A E Germenis and V Karanikas
Immunol Cell Biol 85: 55-59; advance online publication, November 28, 2006; doi:10.1038/sj.icb.7100006
Outstanding Observations
Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH) cell lineage is induced by IL-12 FREE
Cindy S Ma, Santi Suryani, Danielle T Avery, Anna Chan, Ralph Nanan, Brigitte Santner-Nanan, Elissa K Deenick and Stuart G Tangye
Immunol Cell Biol advance online publication, September 1, 2009; doi:10.1038/icb.2009.64
Allogeneic stromal cell implantation in brain tissue leads to robust microglial activation FREE
Bart R Tambuyzer, Irene Bergwerf, Nathalie De Vocht, Kristien Reekmans, Jasmijn Daans, Philippe G Jorens, Herman Goossens, Dirk K Ysebaert, Shyama Chatterjee, Eric Van Marck, Zwi N Berneman and Peter Ponsaerts
Immunol Cell Biol 87: 267-273; advance online publication, March 17, 2009; doi:10.1038/icb.2009.12
Abstract | Full Text | PDF (386K) | Supplementary information
Inhibition of destructive autoimmune arthritis in Fc
RIIa transgenic mice by small chemical entities FREE
Geoffrey A Pietersz, Patricia L Mottram, Nicholas C van de Velde, Caroline Tan Sardjono, Sandra Esparon, Paul A Ramsland, Gerard Moloney, Jonathan B Baell, Tom D McCarthy, Barry R Matthews, Maree S Powell and P Mark Hogarth
Immunol Cell Biol 87: 3-12; advance online publication, November 25, 2008; doi:10.1038/icb.2008.82
Fetal Hox11 expression patterns predict defective target organs: a novel link between developmental biology and autoimmunity FREE
Anna Lonyai, Shohta Kodama, Douglas Burger and Denise L Faustman
Immunol Cell Biol 86: 301-309; advance online publication, February 26, 2008; doi:10.1038/icb.2008.6
Abstract | Full Text | PDF (436K) | Supplementary information
Axon growth and guidance genes identify T-dependent germinal centre B cells FREE
Di Yu, Matthew C Cook, Dong-Mi Shin, Diego G Silva, Jennifer Marshall, Kai-Michael Toellner, Wendy L Havran, Pico Caroni, Michael P Cooke, Herbert C Morse, Ian CM MacLennan, Christopher C Goodnow and Carola G Vinuesa
Immunol Cell Biol 86: 3-14; advance online publication, October 16, 2007; doi:10.1038/sj.icb.7100123
Abstract | Full Text | PDF (532K) | Supplementary information
