ADVANCE ONLINE PUBLICATION

The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
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November 20 2009

Original Articles

Efficacy and safety of aliskiren in Japanese hypertensive patients with renal dysfunction

Sadayoshi Ito, Noriko Nakura, Stephanie Le Breton and Deborah Keefe

Hypertens Res advance online publication, November 20, 2009; doi:10.1038/hr.2009.175

Renal ACE2 expression and activity is unaltered during established hypertension in adult SHRSP and TGR(mREN2)27

Jelena Kamilic, Inge Hamming, Reinhold Kreutz, Juliane Bolbrinker, Wolf-Eberhard Siems, Ibrahim Nassar, Judith C Sluimer, Thomas Walther, Gerjan J Navis and Harry van Goor

Hypertens Res advance online publication, November 20, 2009; doi:10.1038/hr.2009.191

Telmisartan improves endothelial dysfunction and renal autoregulation in Dahl salt-sensitive rats

Minoru Satoh, Yoshisuke Haruna, Sohachi Fujimoto, Tamaki Sasaki and Naoki Kashihara

Hypertens Res advance online publication, November 20, 2009; doi:10.1038/hr.2009.190

Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension

Takayoshi Tsutamoto, Keizo Nishiyama, Masayuki Yamaji, Chiho Kawahara, Masanori Fujii, Takashi Yamamoto and Minoru Horie

Hypertens Res advance online publication, November 20, 2009; doi:10.1038/hr.2009.192

Accumulation of common polymorphisms is associated with development of hypertension: a 12-year follow-up from the Ohasama study

Yumiko Watanabe, Hirohito Metoki, Takayoshi Ohkubo, Tomohiro Katsuya, Yasuharu Tabara, Masahiro Kikuya, Takuo Hirose, Ken Sugimoto, Kei Asayama, Ryusuke Inoue, Azusa Hara, Taku Obara, Jun Nakura, Katsuhiko Kohara, Kazuhito Totsune, Toshio Ogihara, Hiromi Rakugi, Tetsuro Miki and Yutaka Imai

Hypertens Res advance online publication, November 20, 2009; doi:10.1038/hr.2009.193

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November 13 2009

Commentary

Vascular mechanisms of cognitive impairment: roles of hypertension and subsequent small vessel disease under sympathetic influences

Ichiro Akiguchi and Yasumasa Yamamoto

Hypertens Res advance online publication, November 13, 2009; doi:10.1038/hr.2009.189

Reviews

Reinventing the ACE inhibitors: some old and new implications of ACE inhibition

Kashif Hanif, Hemant K Bid and Rituraj Konwar

Hypertens Res advance online publication, November 13, 2009; doi:10.1038/hr.2009.184

The role of AMP-activated protein kinase in the cardiovascular system

Daisuke Nagata and Yasunobu Hirata

Hypertens Res advance online publication, November 13, 2009; doi:10.1038/hr.2009.187

Original Articles

Prenatal exposure to lipopolysaccharide alters the intrarenal renin–angiotensin system and renal damage in offspring rats

Xue-Qin Hao, Hai-Gang Zhang, Zhi-Bing Yuan, Dan-Li Yang, Li-Yun Hao and Xiao-Hui Li

Hypertens Res advance online publication, November 13, 2009; doi:10.1038/hr.2009.185

Anthropometric measures of increased central and overall adiposity in association with echocardiographic left ventricular hypertrophy

Sérgio Lamego Rodrigues, Marcelo Perim Baldo, Roberto Sá Cunha, Lílian CS Angelo, Alexandre C Pereira, José Eduardo Krieger and José Geraldo Mill

Hypertens Res advance online publication, November 13, 2009; doi:10.1038/hr.2009.188

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November 6 2009

Commentaries

Oxidative stress in the brain and arterial hypertension

Ruy R Campos

Hypertens Res advance online publication, November 6, 2009; doi:10.1038/hr.2009.180

The impact of pulse wave velocity in a Japanese population with metabolic syndrome

Akihiro Hirashiki and Toyoaki Murohara

Hypertens Res advance online publication, November 6, 2009; doi:10.1038/hr.2009.182

Review

The increase in renin during renin inhibition: does it result in harmful effects by the (pro)renin receptor?

AH Jan Danser

Hypertens Res advance online publication, November 6, 2009; doi:10.1038/hr.2009.186

Original Article

Phenylephrine induces elevated RhoA activation and smooth muscle alpha-actin expression in Pkd2 +/- vascular smooth muscle cells

Hui Du, Xiangling Wang, Jun Wu and Qi Qian

Hypertens Res advance online publication, November 6, 2009; doi:10.1038/hr.2009.173

Correspondence

Response to Thornton

Hideyasu Kiyomoto and Tadashi Sofue

Hypertens Res advance online publication, November 6, 2009; doi:10.1038/hr.2009.183

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October 30 2009

Original Articles

Posterior paralimbic and frontal metabolite impairments in asymptomatic hypertension with different treatment outcomes

José M García Santos, Luis J Fuentes, Juan B Vidal, Andrés Carrillo, Martirio Antequera, Guillermo Campoy, Carmen Antúnez, Silvia Torres del Río, Julia García-Sevilla and Ginés Ortega

Hypertens Res advance online publication, October 30, 2009; doi:10.1038/hr.2009.176

Melatonin for nondippers with coronary artery disease: assessment of blood pressure profile and heart rate variability

Tomasz Rechcin acuteski, Ewa Trzos, Karina Wierzbowska-Drabik, Maria Krzemin acuteska-Pakul strokea and Mal strokegorzata Kurpesa

Hypertens Res advance online publication, October 30, 2009; doi:10.1038/hr.2009.174

Azelnidipine, a long-acting calcium channel blocker, could control hypertension without decreasing cerebral blood flow in post-ischemic stroke patients. A 123I-IMP SPECT follow-up study

Masaki Watanabe, Teruyuki Hirano, Sadahisa Okamoto, Shinya Shiraishi, Seiji Tomiguchi and Makoto Uchino

Hypertens Res advance online publication, October 30, 2009; doi:10.1038/hr.2009.179

ALDH2 genetic polymorphism and the risk of type II diabetes mellitus in CAD patients

Feng Xu, Yuguo Chen, Ruijuan Lv, He Zhang, Hongbo Tian, Yuan Bian, Jinbo Feng, Yi Sun, Ruijian Li, Rong Wang and Yun Zhang

Hypertens Res advance online publication, October 30, 2009; doi:10.1038/hr.2009.178

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October 23 2009

Commentaries

The ideal combination of anti-hypertensive drugs

Jitsuo Higaki

Hypertens Res advance online publication, October 23, 2009; doi:10.1038/hr.2009.170

Central blood pressure, arterial stiffness and the heart in hypertensive patients

Katsuhiko Kohara

Hypertens Res advance online publication, October 23, 2009; doi:10.1038/hr.2009.171

Original Article

Abnormal nocturnal blood pressure profile is associated with mild cognitive impairment in the elderly: the J-SHIPP study

Haiyan Guo, Yasuharu Tabara, Michiya Igase, Miyuki Yamamoto, Namiko Ochi, Tomoko Kido, Eri Uetani, Keiko Taguchi, Tetsuro Miki and Katsuhiko Kohara

Hypertens Res advance online publication, October 23, 2009; doi:10.1038/hr.2009.172

Correspondence

Preclinical cardiovascular abnormalities in patients in early stages of renal disease without nephrotic syndrome

Pasquale Esposito, Vittorio Palmieri, Paola Migliaresi, Salvatore Pezzullo, Stefania Martino and Mario M Balletta

Hypertens Res advance online publication, October 23, 2009; doi:10.1038/hr.2009.141

Angiotensin antagonists could increase urine production and drinking in order to decrease renal problems in diabetes and hypertension

Simon N Thornton

Hypertens Res advance online publication, October 23, 2009; doi:10.1038/hr.2009.177

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October 16 2009

Commentaries

Blood pressure differences by race: the importance of assessing lifestyle

Atsushi Hozawa and Hirotsugu Ueshima

Hypertens Res advance online publication, October 16, 2009; doi:10.1038/hr.2009.167

Home blood pressure monitoring, even by the elderly, may save a kidney

Hiroyuki Terawaki

Hypertens Res advance online publication, October 16, 2009; doi:10.1038/hr.2009.169

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October 9 2009

Commentaries

Epigenetics, essential hypertension and renin–angiotensin system upregulation in the offspring of water-deprived pregnant rats

Richard M Millis

Hypertens Res advance online publication, October 9, 2009; doi:10.1038/hr.2009.168

Risk-prediction tools for cardiovascular disease based on Japanese cohort studies

Tomonori Okamura and Aya Higashiyama

Hypertens Res advance online publication, October 9, 2009; doi:10.1038/hr.2009.166

Review

The relationship between apolipoprotein E alt epsilon2/alt epsilon3/alt epsilon4 polymorphisms and hypertension: a meta-analysis of six studies comprising 1812 cases and 1762 controls

Wenquan Niu, Yue Qi, Yuesheng Qian, Pingjin Gao and Dingliang Zhu

Hypertens Res advance online publication, October 9, 2009; doi:10.1038/hr.2009.164

Original Articles

A randomized, double-blind, four-arm parallel-group study of the efficacy and safety of azelnidipine and olmesartan medoxomil combination therapy compared with each monotherapy in Japanese patients with essential hypertension: the REZALT study

Toshio Ogihara, Takao Saruta, Kazuyuki Shimada and Kizuku Kuramoto

Hypertens Res advance online publication, October 9, 2009; doi:10.1038/hr.2009.163

Prognostic significance of home blood pressure control on renal and cardiovascular outcomes in elderly patients with chronic kidney disease

Tomonari Okada, Toshiyuki Nakao, Hiroshi Matsumoto, Yume Nagaoka, Ryo Tomaru, Hideaki Iwasawa and Toshikazu Wada

Hypertens Res advance online publication, October 9, 2009; doi:10.1038/hr.2009.165

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September 25 2009

Original Articles

Prenatal dehydration alters renin–angiotensin system associated with angiotensin-increased blood pressure in young offspring

Junchang Guan, Caiping Mao, Feichao Xu, Chunsong Geng, Liyan Zhu, Aiqing Wang and Zhice Xu

Hypertens Res advance online publication, September 25, 2009; doi:10.1038/hr.2009.155

Validity and repeatability of the Vicorder apparatus: a comparison with the SphygmoCor device

Stacey S Hickson, Mark Butlin, Jeremy Broad, Alberto P Avolio, Ian B Wilkinson and Carmel M McEniery

Hypertens Res advance online publication, September 25, 2009; doi:10.1038/hr.2009.154

Enhanced hypertension prevalence in non-Han Chinese minorities from Xinjiang Province, China

Zhensui Lu, Zhenhong Lu, Yanling Zhu, Zhaoyang Yan, Xiaoquan Liu, Shigui Yan and Guo-Ping Shi

Hypertens Res advance online publication, September 25, 2009; doi:10.1038/hr.2009.159

Comparison of central blood pressure and cardio-ankle vascular index for association with cardiac function in treated hypertensive patients

Hisashi Masugata, Shoichi Senda, Hiroyuki Okuyama, Koji Murao, Michio Inukai, Naohisa Hosomi, Kazushi Yukiiri, Akira Nishiyama, Masakazu Kohno and Fuminori Goda

Hypertens Res advance online publication, September 25, 2009; doi:10.1038/hr.2009.157

Uncontrolled hypertension based on morning and evening home blood pressure measurements from the J-HOME study

Taku Obara, Kie Ito, Takayoshi Ohkubo, Taku Shibamiya, Takahiro Shinki, Manami Nakashita, Azusa Hara, Hirohito Metoki, Ryusuke Inoue, Kei Asayama, Masahiro Kikuya, Nariyasu Mano and Yutaka Imai the J-HOME Study Group

Hypertens Res advance online publication, September 25, 2009; doi:10.1038/hr.2009.152

Metabolic syndrome is a significant and independent risk factor for increased arterial stiffness in Japanese subjects

Hiroki Satoh, Reiko Kishi and Hiroyuki Tsutsui

Hypertens Res advance online publication, September 25, 2009; doi:10.1038/hr.2009.158

Evaluation of arterial stiffness in morning hypertension under high-dose valsartan compared to valsartan plus low-dose diuretic

Takeshi Takami

Hypertens Res advance online publication, September 25, 2009; doi:10.1038/hr.2009.156

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September 18 2009

Original Articles

Olmesartan reduces oxidative stress in the brain of stroke-prone spontaneously hypertensive rats assessed by an in vivo ESR method

Shuichiro Araki, Yoshitaka Hirooka, Takuya Kishi, Keiji Yasukawa, Hideo Utsumi and Kenji Sunagawa

Hypertens Res advance online publication, September 18, 2009; doi:10.1038/hr.2009.160

Development and validation of a cardiovascular risk prediction model for Japanese: the Hisayama study

Hisatomi Arima, Koji Yonemoto, Yasufumi Doi, Toshiharu Ninomiya, Jun Hata, Yumihiro Tanizaki, Masayo Fukuhara, Kiyoshi Matsumura, Mitsuo Iida and Yutaka Kiyohara

Hypertens Res advance online publication, September 18, 2009; doi:10.1038/hr.2009.161

Misregulation of the arginase pathway in tissues of spontaneously hypertensive rats

Teddy Bagnost, Alain Berthelot, Magalie Alvergnas, Carole Miguet-Alfonsi, Claire André, Yves Guillaume and Céline Demougeot

Hypertens Res advance online publication, September 18, 2009; doi:10.1038/hr.2009.153

Safety and benefits of a tablet combining losartan and hydrochlorothiazide in Japanese diabetic patients with hypertension

Kenichiro Kinouchi, Atsuhiro Ichihara, Mariyo Sakoda, Asako Kurauchi-Mito and Hiroshi Itoh

Hypertens Res advance online publication, September 18, 2009; doi:10.1038/hr.2009.162

Association of PLA2G7 polymorphisms with carotid atherosclerosis in hypertensive Japanese

Yoshikazu Miwa, Kei Kamide, Shin Takiuchi, Masayoshi Yoshii, Takeshi Horio, Chihiro Tanaka, Mariko Banno, Toshiyuki Miyata and Yuhei Kawano

Hypertens Res advance online publication, September 18, 2009; doi:10.1038/hr.2009.151

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