Hypertension Research

TABLE 1

FROM:

Antihypertensive, antidyslipidemic and endothelial modulating activities of Orchis mascula

Nauman Aziz, Malik Hassan Mehmood, Hasan Salman Siddiqi, Saf-ur-Rehman Mandukhail, Fatima Sadiq, Wajiha Maan and Anwarul Hassan Gilani

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Table 1. Effects of Orchis mascula (OM) on blood pressure, serum lipids and glucose in SHR

Parameters WKY SHR SHR+Orchis mascula
Systolic BP (mm Hg)140.7plusminus3.4203.4plusminus7.13†† 174.2plusminus9.63*
Heart rate (b.p.m.)322.1plusminus11.7331.3plusminus6.02333.3plusminus8.28
Total cholesterol (mg per 100 ml)110.9plusminus7.890.3plusminus7.769.51plusminus11.62
HDL-C (mg per 100 ml)93.9plusminus6.668.3plusminus7.1 63.51plusminus10.75
LDL-C (mg per 100 ml)17plusminus3.621.9plusminus3.55.99plusminus1.27*
Triglycerides (mg per 100 ml)80.42plusminus4.093.84plusminus5.7 29.28plusminus6.99**
Atherogenic index0.183plusminus0.040.36plusminus0.08†† 0.096plusminus0.017*
Glucose (mg per 100 ml)116plusminus8.989.6plusminus12.097.78plusminus23.74

 Abbreviations: ANOVA, analysis of variance; BP, blood pressure; b.p.m., beats per minute; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SHR, spontaneously hypertensive rat; WKY, Wistar Koyoto.

 One-way ANOVA followed by Tukey's post-test. WKY rats served as normotensive controls.

 Values shown are meanplusminuss.e.m. of 7–10 determinations

  * P<0.05; ** P<0.001 compared with SHR control.

  P<0.05; †† P<0.01 compared with normotensive WKY control.

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