Gene Therapy TOP TEN

The top ten charts the articles that have been downloaded most often, in HTML format, from the Gene Therapy website in recent weeks. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.

October 2009

1. Progress and prospects: human artificial chromosomes

   S Macnab and A Whitehouse

   doi:10.1038/gt.2009.102

   Abstract | Full Text | PDF

2. Stem cells, ribozymes and HIV FREE

   J C Burnett and J J Rossi

   doi:10.1038/gt.2009.86

   Abstract | Full Text | PDF

3. Fragile X mental retardation protein replacement restores hippocampal synaptic function in a mouse model of fragile X syndrome

   Z Zeier, A Kumar, K Bodhinathan, J A Feller, T C Foster and D C Bloom

   doi:10.1038/gt.2009.83

   Abstract | Full Text | PDF

4. Progress and Prospects: prospects of repeated pulmonary administration of viral vectors

   P L Sinn, E R Burnight and P B McCray

   doi:10.1038/gt.2009.87

   Abstract | Full Text | PDF

5. Engineering ligand-responsive gene-control elements: lessons learned from natural riboswitches

   K H Link and R R Breaker

   doi:10.1038/gt.2009.81

   Abstract | Full Text | PDF

6. A fine balance: an autoregulatory gene therapy approach to treat obesity and achieve energy homeostasis FREE

   S L Samson, M Kohjima and L Chan

   doi:10.1038/gt.2009.88

   Abstract | Full Text | PDF

7. Lister strain of vaccinia virus armed with endostatin–angiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer

   J R Tysome, A Briat, G Alusi, F Cao, D Gao, J Yu, P Wang, S Yang, Z Dong, S Wang, L Deng, J Francis, T Timiryasova, I Fodor, N R Lemoine and Y Wang

   doi:10.1038/gt.2009.74

   Abstract | Full Text | PDF | Supplementary information

8. An immobilized nanoparticle-based platform for efficient gene knockdown of targeted cells in the circulation

   Z Huang and M R King

   doi:10.1038/gt.2009.76

   Abstract | Full Text | PDF

9. Embryo and stem cell research in the United States: history and politics FREE

   doi:10.1038/sj.gt.3301744

   Abstract | Full Text | PDF

10. PML has a predictive role in tumor cell permissiveness to interferon-sensitive oncolytic viruses

    P T Sobol, J L Hummel, R M Rodrigues and K L Mossman

    doi:10.1038/gt.2009.68

    Abstract | Full Text | PDF | Supplementary information

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• Cancer Gene Therapy
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• Oncogene
• Nature Medicine
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• Molecular Therapy