PROGRESS AND PROSPECTS

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2009

May

Progress and prospects: techniques for site-directed mutagenesis in animal models FREE

Z Yan, X Sun and J F Engelhardt

Gene Ther 16: 581-588; doi:10.1038/gt.2009.16; published online 19 February 2009

February

Progress and Prospects: The design and production of plasmid vectors

D R Gill, I A Pringle and S C Hyde

Gene Ther 16: 165-171; doi:10.1038/gt.2008.183; published online 8 January 2009

January

Progress & Prospects: Gene therapy in aging FREE

S I S Rattan and R Singh

Gene Ther 16: 3-9; doi:10.1038/gt.2008.166; published online 13 November 2008

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2008

November

Progress and prospects: Zinc-finger nucleases as gene therapy agents FREE

D Carroll

Gene Ther 15: 1463-1468; doi:10.1038/gt.2008.145; published online 11 September

September

Progress and prospects: genetic engineering in xenotransplantation

S Le Bas-Bernardet, I Anegon and G Blancho

Gene Ther 15: 1247-1256; doi:10.1038/gt.2008.119

August

Gene therapy progress and prospects: synthetic polymer-based systems

D Schaffert and E Wagner

Gene Ther 15: 1131-1138; doi:10.1038/gt.2008.105; published online 5 June 2008

July

Progress and prospects: gene therapy for mitochondrial DNA disease

D S Kyriakouli, P Boesch, R W Taylor and R N Lightowlers

Gene Ther 15: 1017-1023; doi:10.1038/gt.2008.91; published online 22 May 2008

June

Gene therapy progress and prospects cancer: oncolytic viruses

T-C Liu and D Kirn

Gene Ther 15: 877-884; doi:10.1038/gt.2008.72; published online 17 April 2008

April

Progress and prospects: gene therapy for genetic diseases with helper-dependent adenoviral vectors FREE

N Brunetti-Pierri and P Ng

Gene Ther 15: 553-560; doi:10.1038/gt.2008.14; published online 21 February 2008

March

Progress and prospects: gene therapy for performance and appearance enhancement

M Kiuru and R G Crystal

Gene Ther 15: 329-337; doi:10.1038/sj.gt.3303100; published online 24 January 2008

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2007

December

Progress and Prospects: targeted gene alteration (TGA)

H Parekh-Olmedo and E B Kmiec

Gene Ther 14: 1675-1680; doi:10.1038/sj.gt.3303053; published online 1 November

November

Progress and Prospects: Gene Therapy Clinical Trials (Part 2)

U Griesenbach

Gene Ther 14: 1555-1563; doi:10.1038/sj.gt.3303033

October

Progress and Prospects: Gene Therapy Clinical Trials (Part 1)

Eric Alton

Gene Ther 14: 1439-1447; doi:10.1038/sj.gt.3303001

July

Progress and prospects: RNA-based therapies for treatment of HIV infection

L Scherer, J J Rossi and M S Weinberg

Gene Ther 14: 1057-1064; doi:10.1038/sj.gt.3302977

May

Gene therapy progress and prospects: therapeutic angiogenesis for ischemic cardiovascular disease

K A Vincent, C Jiang, I Boltje and R A Kelly

Gene Ther 14: 781-789; doi:10.1038/sj.gt.3302953

March

Gene therapy progress and prospects: Ultrasound for gene transfer FREE

C M H Newman and T Bettinger

Gene Ther 14: 465-475; doi:10.1038/sj.gt.3302925

February

Gene therapy progress and prospects: RNA aptamers

N S Que-Gewirth and B A Sullenger

Gene Ther 14: 283-291; doi:10.1038/sj.gt.3302900

January

Gene therapy progress and prospects: Hydrodynamic gene delivery

H Herweijer and J A Wolff

Gene Ther 14: 99-107; doi:10.1038/sj.gt.3302891; published online 30 November 2006

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2006

December

Gene therapy progress and prospects: Duchenne muscular dystrophy

K Foster, H Foster and J G Dickson

Gene Ther 13: 1677-1685; doi:10.1038/sj.gt.3302877; published online 26 October 2006

November

Gene therapy progress and prospects: the skin - easily accessible, but still far away

U R Hengge

Gene Ther 13: 1555-1563; doi:10.1038/sj.gt.3302855; published online 7 September 2006

October

Progress and prospects: gene transfer into embryonic stem cells

F Yates and G Q Daley

Gene Ther 13: 1431-1439; doi:10.1038/sj.gt.3302854

September

Gene therapy progress and prospects: non-viral gene therapy by systemic delivery

S-D Li and L Huang

Gene Ther 13: 1313-1319; doi:10.1038/sj.gt.3302838

August

Gene therapy progress and prospects: the eye

J W B Bainbridge, M H Tan and R R Ali

Gene Ther 13: 1191-1197; doi:10.1038/sj.gt.3302812

July

Gene therapy progress and prospects: cystic fibrosis

U Griesenbach, D M Geddes and E W F W Alton on behalf of the UK Cystic Fibrosis Gene Therapy Consortium

Gene Ther 13: 1061-1067; doi:10.1038/sj.gt.3302809

May

Gene Therapy Progress and Prospects - Vectorology: design and production of expression cassettes in AAV vectors

C Le Bec and A M Douar

Gene Ther 13: 805-813; doi:10.1038/sj.gt.3302724; published online 2 February 2006

April

Progress and prospects: Cell based regenerative therapy for cardiovascular disease

E D de Muinck, C Thompson and M Simons

Gene Ther 13: 659-671; doi:10.1038/sj.gt.3302680; published online 1 December 2005

February

Gene therapy progress and prospects: magnetic nanoparticle-based gene delivery

J Dobson

Gene Ther 13: 283-287; doi:10.1038/sj.gt.3302720

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2005

December

Gene Therapy Progress and Prospects: In tissue engineering FREE

J Polak and L Hench

Gene Ther 12: 1725-1733; doi:10.1038/sj.gt.3302651; published online 22 September 2005

November

Gene Therapy Progress and Prospects: Fetal gene therapy - first proofs of concept - some adverse effects FREE

C Coutelle, M Themis, S N Waddington, S M K Buckley, L G Gregory, M S Nivsarkar, A L David, D Peebles, B Weisz and C Rodeck

Gene Ther 12: 1601-1607; doi:10.1038/sj.gt.3302632; published online 1 September 2005

October

Gene Therapy Progress and Prospects: Reprograming gene expression by trans-splicing

L G Mitchell and G J McGarrity

Gene Ther 12: 1477-1485; doi:10.1038/sj.gt.3302596; published online 25 August 2005

September

Gene Therapy Progress and Prospects: Viral trafficking during infection FREE

E M Campbell and T J Hope

Gene Ther 12: 1353-1359; doi:10.1038/sj.gt.3302585

August

Gene Therapy Progress and Prospects: Stem cell plasticity

K Kashofer and D Bonnet

Gene Ther 12: 1229-1234; doi:10.1038/sj.gt.3302571; published online 23 June 2005

July

Gene Therapy Progress and Prospects: Development of improved lentiviral and retroviral vectors - design, biosafety, and production

P L Sinn, S L Sauter and P B McCray Jr

Gene Ther 12: 1089-1098; doi:10.1038/sj.gt.3302570; published online 23 June 2005

May

Gene Therapy Progress and Prospects: Recent progress in transgene and RNAi expression cassettes

C R Ill and H C Chiou

Gene Ther 12: 795-802; doi:10.1038/sj.gt.3302524; Published online 7 April 2005

April

Gene therapy progress and prospects: targeted gene repair

H Parekh-Olmedo, L Ferrara, E Brachman and E B Kmiec

Gene Ther 12: 639-646; doi:10.1038/sj.gt.3302511

March

Gene therapy progress and prospects: Novel gene therapy approaches for AIDS

R Wolkowicz and G P Nolan

Gene Ther 12: 467-476; doi:10.1038/sj.gt.3302488; Published online 10 February 2005

January

Gene Therapy Progress and Prospects: Gene therapy for diabetes mellitus

V Yechoor and L Chan

Gene Ther 12: 101-107; doi:10.1038/sj.gt.3302412; Published online 21 October 2004

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2004

December

Gene Therapy Progress and Prospects: Episomally maintained self-replicating systems FREE

M Conese, C Auriche and F Ascenzioni

Gene Ther 11: 1735-1741; doi:10.1038/sj.gt.3302362; Published online 23 September 2004

November

Gene Therapy Progress and Prospects: Bringing gene therapy into medical practice: the evolution of international ethics and the regulatory environment FREE

J Spink and D Geddes

Gene Ther 11: 1611-1616; doi:10.1038/sj.gt.3302354; Published online 23 September 2004

September

Gene Therapy Progress and Prospects: Electroporation and other physical methods FREE

D J Wells

Gene Ther 11: 1363-1369; doi:10.1038/sj.gt.3302337; Published online 5 August 2004

August

Gene Therapy Progress and Prospects. Downregulating gene expression: the impact of RNA interference FREE

N J Caplen

Gene Ther 11: 1241-1248; doi:10.1038/sj.gt.3302324

May

Gene Therapy Progress and Prospects: Recombinant adeno-associated virus (rAAV) vectors FREE

T R Flotte

Gene Ther 11: 805-810; doi:10.1038/sj.gt.3302233; Published online 25 March 2004

April

Gene therapy progress and prospects: transcription regulatory systems FREE

C Toniatti, H Bujard, R Cortese and G Ciliberto

Gene Ther 11: 649-657; doi:10.1038/sj.gt.3302251; Published online 26 February 2004

March

Gene Therapy Progress and Prospects: cancer gene therapy using tumour suppressor genes FREE

IA McNeish, SJ Bell and NR Lemoine

Gene Ther 11: 497-503; doi:10.1038/sj.gt.3302238; Published online 5 February 2004

January

Gene Therapy Progress and Prospects: Noninvasive imaging of gene therapy in living subjects FREE

JJ Min and SS Gambhir

Gene Ther 11: 115-125; doi:10.1038/sj.gt.3302191

Top

2003

November

Gene therapy progress and prospects: gene therapy for severe combined immunodeficiency FREE

H B Gaspar, S Howe and A J Thrasher

Gene Ther 10: 1999-2004; doi:10.1038/sj.gt.3302150

September

Gene therapy progress and prospects: Parkinson's disease FREE

E A Burton, J C Glorioso and D J Fink

Gene Ther 10: 1721-1727; doi:10.1038/sj.gt.3302116

August

Gene therapy progress and prospects: gene therapy of lysosomal storage disorders FREE

S H Cheng and A E Smith

Gene Ther 10: 1275-1281; doi:10.1038/sj.gt.3302092

July

Gene therapy progress and prospects: adenoviral vectors FREE

J A St George

Gene Ther 10: 1135-1141; doi:10.1038/sj.gt.3302071

June

Gene therapy Progress and Prospects: Gene therapy for the hemophilias FREE

Christopher E Walsh MD, Ph,D

Gene Ther 10: 999-1003; doi:10.1038/sj.gt.3302024

April

Gene Therapy Progress and Prospects: Gene therapy in organ transplantation FREE

J Bagley and J Iacomini

Gene Ther 10: 605-611; doi:10.1038/sj.gt.3302020

March

Progress and prospects: naked DNA gene transfer and therapy FREE

H Herweijer and J A Wolff

Gene Ther 10: 453-458; doi:10.1038/sj.gt.3301983

February

Gene therapy progress and prospects: therapeutic angiogenesis for limb and myocardial ischemia FREE

T A Khan, F W Sellke and R J Laham

Gene Ther 10: 285-291; doi:10.1038/sj.gt.3301969

January

Gene Therapy Progress and Prospects: Alpha-1 antitrypsin FREE

A A Stecenko and K L Brigham

Gene Ther 10: 95-99; doi:10.1038/sj.gt.3301947

Top

2002

December

Gene Therapy Progress and Prospects: Nonviral vectors FREE

T Niidome and L Huang

Gene Ther 9: 1647-1652; doi:10.1038/sj.gt.3301923

November

Post-intervention vessel remodeling FREE

J Rutanen, H Puhakka and S Ylä-Herttuala

Gene Ther 9: 1487-1491; doi:10.1038/sj.gt.3301866

October

Gene Therapy Progress and Prospects: Cystic fibrosis FREE

U Griesenbach, S Ferrari, D M Geddes and E W F W Alton

Gene Ther 9: 1344-1350; doi:10.1038/sj.gt.3301791

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