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August 1999, Volume 6, Number 8

Table of Contents

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Editorial
Opportunities and challenges in targeting genes for therapy FREE
D C Gruenert
Abstract  |  Full text  |  PDF 1347
Perspective
Adenoviral vectors: prospects for gene delivery to the central nervous system FREE
Robin J Parks & Jonathan L Bramson
Abstract  |  Full text  |  PDF 1349
Papers
A model for long-term transgene expression in spinal cord regeneration studies FREE
M T O'Leary & H M Charlton
Abstract  |  Full text  |  PDF 1351
Adenoviral vectors for in vivo gene delivery to oligodendrocytes: transgene expression and cytopathic consequences FREE
R J M Franklin, M M Quick & G Haase
Abstract  |  Full text  |  PDF 1360
Inflammatory responses and their impact on bold beta-galactosidase transgene expression following adenovirus vector delivery to the primate caudate nucleus FREE
M S Lawrence, H G Foellmer, J D Elsworth, J H Kim, C Leranth, D A Kozlowski, A L M Bothwell, B L Davidson, M C Bohn & D E Redmond Jr
Abstract  |  Full text  |  PDF 1368
Improved packing of poly(ethylenimine)/DNA complexes increases transfection efficiency FREE
W T Godbey, K K Wu, G J Hirasaki & A G Mikos
Abstract  |  Full text  |  PDF 1380
Distribution of retroviral vectors and vector producer cells using two routes of administration in rats FREE
M Kaloss, M Linscott, C Wey, P Lu, Z Long, G J McGarrity, E Otto & R M Lyons
Abstract  |  Full text  |  PDF 1389
Human serum-resistant retroviral vector particles from galactosyl (alpha1-3) galactosyl containing nonprimate cell lines FREE
J M Mason, D E Guzowski, L O Goodwin, D Porti, K C Cronin, S Teichberg & R G Pergolizzi
Abstract  |  Full text  |  PDF 1397
Local and distant transfection of mdx muscle fibers with dystrophin and LacZ genes delivered in vivo by synthetic microspheres FREE
A Baranov, P Glazkov, A Kiselev, O Ostapenko, V Mikhailov, T Ivaschenko, V Sabetsky & V Baranov
Abstract  |  Full text  |  PDF 1406
Enhancement of tumor ablation by a selected HSV-1 thymidine kinase mutant FREE
M S Kokoris, P Sabo, E T Adman & M E Black
Abstract  |  Full text  |  PDF 1415
Cellular redox state alters recombinant adeno-associated virus transduction through tyrosine phosphatase pathways FREE
S Sanlioglu & J F Engelhardt
Abstract  |  Full text  |  PDF 1427
Stabilized plasmid-lipid particles for regional gene therapy: formulation and transfection properties FREE
Y P Zhang, L Sekirov, E G Saravolac, J J Wheeler, P Tardi, K Clow, E Leng, R Sun, P R Cullis & P Scherrer
Abstract  |  Full text  |  PDF 1438
The effect of CpG sequences on the B cell response to a viral glycoprotein encoded by a plasmid vector FREE
S Pasquini, H Deng, S T Reddy, W Giles-Davis & H C J Ertl
Abstract  |  Full text  |  PDF 1448
Adenovirus-mediated expresssion of the murine ecotropic receptor facilitates transduction of human hematopoietic cells with an ecotropic retroviral vector FREE
A C Nathwani, D A Persons, S C Stevenson, P Frare, A McClelland, A W Nienhuis & E F Vanin
Abstract  |  Full text  |  PDF 1456
Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM FREE
H J Haisma, H M Pinedo, A van Rijswijk, I van der Meulen-Muileman, B A Sosnowski, W Ying, V W van Beusechem, B W Tillman, W R Gerritsen & D T Curiel
Abstract  |  Full text  |  PDF 1469
Anti-tumour activity against B16-F10 melanoma with a GM-CSF secreting allogeneic tumour cell vaccine FREE
J Kayaga, B E Souberbielle, N Sheikh, W J W Morrow, T Scott-Taylor, R Vile & A G Dalgleish
Abstract  |  Full text  |  PDF 1475
Brief communication
pCOR: a new design of plasmid vectors for nonviral gene therapy FREE
F Soubrier, B Cameron, B Manse, S Somarriba, C Dubertret, G Jaslin, G Jung, C Le Caer, D Dang, J M Mouvault, D Scherman, J F Mayaux & J Crouzet
Abstract  |  Full text  |  PDF 1482
A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents FREE
J Jelinek, J A Rafferty, R Cmejla, M Hildinger, D Chinnasamy, L S Lashford, W Ostertag, G P Margison, T M Dexter, L J Fairbairn & C Baum
Abstract  |  Full text  |  PDF 1489
August 1999, Volume 6, Number 8
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