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May 1999, Volume 6, Number 5

Table of Contents

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Editorial
Who's afraid of replication-competent adenoviruses? FREE
F J Fallaux, A J van der Eb & R C Hoeben
Abstract  |  Full text  |  PDF 709
Perspective
Apoptin: nuclear switch triggers cancer cell death FREE
Dr A L Murphy
Abstract  |  Full text  |  PDF 713
Papers
Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system FREE
L-J Chang, V Urlacher, T Iwakuma, Y Cui & J Zucali
Abstract  |  Full text  |  PDF 715
Rapid clearance of syngeneic transplanted hepatocytes following transduction with E-1-deleted adenovirus indicates early host immune responses and offers novel ways for studying viral vector, target cell and host interactions FREE
S Gagandeep, M Ott, R P Sokhi & S Gupta
Abstract  |  Full text  |  PDF 729
Needle injection catheter delivery of the gene for an antibacterial agent inhibits neointimal formation FREE
S Nikol, T Y Huehns, E Krausz, S Armeanu, M G Engelmann, D Winder, B Salmons & B Hoefling
Abstract  |  Full text  |  PDF 737
Transient cyclophosphamide treatment before intraportal readministration of an adenoviral vector can induce re-expression of the original gene construct in rat liver FREE
S Kuriyama, K Tominaga, M Kikukawa, T Tsujimoto, T Nakatani, H Tsujinoue, H Okuda, S Nagao, A Mitoro, H Yoshiji & H Fukui
Abstract  |  Full text  |  PDF 749
Adenovirus-mediated delivery of the Gax transcription factor to rat carotid arteries inhibits smooth muscle proliferation and induces apoptosis FREE
H Perlman, Z Luo, K Krasinski, A Le Roux, A Mahfoudi, R C Smith, D Branellec & K Walsh
Abstract  |  Full text  |  PDF 758
Nitroreductase-mediated cell ablation is very rapid and mediated by a p53-independent apoptotic pathway FREE
W Cui, B Gusterson & A J Clark
Abstract  |  Full text  |  PDF 764
Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein FREE
G J Prud'homme & Y Chang
Abstract  |  Full text  |  PDF 771
Induction of tumor immunity by autologous B lymphoma cells expressing a genetically engineered idiotype FREE
M Selmayr, J Strehl, J-P Kremer, E Kremmer, A Doenecke, M Hallek, H Menzel, K Thielemans, S Thierfelder & R Mocikat
Abstract  |  Full text  |  PDF 778
Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals FREE
D C MacLaren, S S Gambhir, N Satyamurthy, J R Barrio, S Sharfstein, T Toyokuni, L Wu, A J Berk, S R Cherry, M E Phelps & H R Herschman
Abstract  |  Full text  |  PDF 785
Myoblast transplantations lead to the expression of the laminin alpha2 chain in normal and dystrophic (dy/dy) mouse muscles FREE
J-T Vilquin, B Guérette, J Puymirat, D Yaffe, F M S Tomé, M Fardeau, M Fiszman, K Schwartz & J P Tremblay
Abstract  |  Full text  |  PDF 792
Targeting an adenoviral gene vector to cytokine-activated vascular endothelium via E-selectin FREE
O A Harari, T J Wickham, C J Stocker, I Kovesdi, D M Segal, T Y Huehns, C Sarraf & D O Haskard
Abstract  |  Full text  |  PDF 801
Potent antitumor effects mediated by local expression of the mature form of the interferon-bold gamma inducing factor, interleukin-18 (IL-18) FREE
T Osaki, W Hashimoto, A Gambotto, H Okamura, P D Robbins, M Kurimoto, M T Lotze & H Tahara
Abstract  |  Full text  |  PDF 808
Allograft transduction of IL-10 prolongs survival following orthotopic liver transplantation FREE
K Shinozaki, H Yahata, H Tanji, T Sakaguchi, H Ito & K Dohi
Abstract  |  Full text  |  PDF 816
Gene transfer mediated by fusion protein hemagglutinin reconstituted in cationic lipid vesicles FREE
P Schoen, A Chonn, P R Cullis, J Wilschut & P Scherrer
Abstract  |  Full text  |  PDF 823
Intratumoral delivery of IL-12 gene by polyvinyl polymeric vector system to murine renal and colon carcinoma results in potent antitumor immunity FREE
S K Mendiratta, A Quezada, M Matar, J Wang, H L Hebel, S Long, J L Nordstrom & F Pericle
Abstract  |  Full text  |  PDF 833
Sustained gene expression in transplanted skin fibroblasts in rats FREE
M Q Wei, D V Lejnieks, N Ramesh, S Lau, J Seppen & W R A Osborne
Abstract  |  Full text  |  PDF 840
Human PBMC-derived dendritic cells transduced with an adenovirus vector induce cytotoxic T-lymphocyte responses against a vector-encoded antigen in vitro FREE
J Diao, J A Smythe, C Smyth, P B Rowe & I E Alexander
Abstract  |  Full text  |  PDF 845
Adenovirus-mediated tissue-targeted expression of the HSVtk gene for the treatment of breast cancer FREE
L M Anderson, S Swaminathan, I Zackon, A-K Tajuddin, B Thimmapaya & S A Weitzman
Abstract  |  Full text  |  PDF 854
Cytotoxic T lymphocyte response against non-immunoselected tumor antigens predicts the outcome of gene therapy with IL-12-transduced tumor cell vaccine FREE
M Rodolfo, C Zilocchi, B Cappetti, G Parmiani, C Melani & M P Colombo
Abstract  |  Full text  |  PDF 865
Photodynamic treatment of adenoviral vectors with visible light: an easy and convenient method for viral inactivation FREE
F H E Schagen, A C E Moor, S C Cheong, S J Cramer, H van Ormondt, A J van der Eb, T M A R Dubbelman & R C Hoeben
Abstract  |  Full text  |  PDF 873
Specific tumor-cell killing with adenovirus vectors containing the apoptin gene FREE
A M Pietersen, M M van der Eb, H J Rademaker, D J M van den Wollenberg, M J W E Rabelink, P J K Kuppen, J H van Dierendonck, H van Ormondt, D Masman, C J H van de Velde, A J van der Eb, R C Hoeben & M H M Noteborn
Abstract  |  Full text  |  PDF 882
CpG DNA and LPS induce distinct patterns of activation in human monocytes FREE
G Hartmann & A M Krieg
Abstract  |  Full text  |  PDF 893
Replication-defective herpes simplex virus vectors for neurotrophic factor gene transfer in vitro and in vivo FREE
P Marconi, M Simonato, S Zucchini, G Bregola, R Argnani, D Krisky, J C Glorioso & R Manservigi
Abstract  |  Full text  |  PDF 904
Targeted RNases: a feasibility study for use in HIV gene therapy FREE
S Singwi, A Ramezani, S F Ding & S Joshi
Abstract  |  Full text  |  PDF 913
Allele replacement: an application that permits rapid manipulation of herpes simplex virus type 1 genomes FREE
B C Horsburgh, M M Hubinette, D Qiang, M L E MacDonald & F Tufaro
Abstract  |  Full text  |  PDF 922
Transgene expression, but not gene delivery, is improved by adhesion-assisted lipofection of hematopoietic cells FREE
H Keller, C Yunxu, G Marit, M Pla, J Reiffers, J Thèze & P Froussard
Abstract  |  Full text  |  PDF 931
Brief communication
Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium FREE
T Hudde, S A Rayner, R M Comer, M Weber, J D Isaacs, H Waldmann, D F P Larkin & A J T George
Abstract  |  Full text  |  PDF 939
Hematopoietic cytokine-inducible gene expression from retroviral vectors FREE
R L Saylors, K C Stine & J Derrick
Abstract  |  Full text  |  PDF 944
Suppression of HIV-1 transcription and replication by a Vpr mutant FREE
B E Sawaya, K Khalili, J Rappaport, D Serio, W Chen, A Srinivasan & S Amini
Abstract  |  Full text  |  PDF 947
May 1999, Volume 6, Number 5
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