Volume 24, Issue 6 (June 2017)


Original Articles

Characterization of retroviral infectivity and superinfection resistance during retrovirus-mediated transduction of mammalian cells Open

J Liao, Q Wei, J Fan, Y Zou, D Song, J Liu, F Liu, C Ma, X Hu, L Li, Y Yu, X Qu, L Chen, X Yu, Z Zhang, C Zhao, Z Zeng, R Zhang, S Yan, T Wu, X Wu, Y Shu, J Lei, Y Li, W Zhang, J Wang, R R Reid, M J Lee, W Huang, J M Wolf, T-C He and J Wang

Gene Ther 24: 333-341; advance online publication, May 4, 2017; doi:10.1038/gt.2017.24

Development of potent class II transactivator gene delivery systems capable of inducing de novo MHC II expression in human cells, in vitro and ex vivo FREE

M L Palma, P Duangkhae, B Douradinha, I F T Viana, P O Rigato, R Dhalia, R B Mailliard, S M Barratt-Boyes, E J M Nascimento, T M Oshiro, A J da Silva Duarte and E T A Marques

Gene Ther 24: 342-352; advance online publication, May 4, 2017; doi:10.1038/gt.2017.25

Potential mechanisms of microRNA-141-3p to alleviate chronic inflammatory pain by downregulation of downstream target gene HMGB1: in vitro and in vivo studies

W-S Shen, X-Q Xu, N-N Zhai, Z-S Zhou, J Shao and Y-H Yu

Gene Ther 24: 353-360; advance online publication, May 25, 2017; doi:10.1038/gt.2017.28


Original Article - Enabling Technologies

Improved gene delivery to adult mouse spinal cord through the use of engineered hybrid adeno-associated viral serotypes FREE

J J Siu, N J Queen, W Huang, F Q Yin, X Liu, C Wang, D M McTigue and L Cao

Gene Ther 24: 361-369; advance online publication, May 4, 2017; doi:10.1038/gt.2017.27


Short Communication

Antigen-presenting cell-targeted lentiviral vectors do not support the development of productive T-cell effector responses: implications for in vivo targeted vaccine delivery FREE

C Goyvaerts, Y De Vlaeminck, D Escors, S Lienenklaus, M Keyaerts, G Raes and K Breckpot

Gene Ther 24: 370-375; advance online publication, May 25, 2017; doi:10.1038/gt.2017.30