Volume 17, Issue 4 (April 2010)



Progress and prospects: nuclear import of nonviral vectors FREE

A P Lam and D A Dean

Gene Ther 17: 439-447; advance online publication, March 4, 2010; doi:10.1038/gt.2010.31

Progress and prospects: Immunobiology of gene therapy for neurodegenerative disease: prospects and risks FREE

M M McMenamin and M J A Wood

Gene Ther 17: 448-458; advance online publication, February 11, 2010; doi:10.1038/gt.2010.2


Original Articles

Vaccination with a potent DNA vaccine targeting B-cell epitopes of hGRP induces prophylactic and therapeutic antitumor activity in vivo  FREE

Lu Yong, Zhang Huiyong, Hou Jing, Wang Huaqian, Hu Xiangbing, Ma Yanjun, Ge Xiaoyu, Huang Li, Yang Yanan, Cao Rongyue, Fan Hao, Liu Jingjing and Wu Jie

Gene Ther 17: 459-468; advance online publication, February 4, 2010; doi:10.1038/gt.2009.165

Dendritic and tumor cell fusions transduced with adenovirus encoding CD40L eradicate B-cell lymphoma and induce a Th17-type response FREE

E Alvarez, E Moga, J Barquinero, J Sierra and J Briones

Gene Ther 17: 469-477; advance online publication, December 10, 2009; doi:10.1038/gt.2009.150

Functional recovery of diabetic mouse hearts by glutaredoxin-1 gene therapy: role of Akt-FoxO-signaling network FREE

I Lekli, S Mukherjee, D Ray, N Gurusamy, Y H Kim, A Tosaki, R M Engelman, Y-S Ho and D K Das

Gene Ther 17: 478-485; advance online publication, February 25, 2010; doi:10.1038/gt.2010.9

AAV-mediated knockdown of Peripherin-2 in vivo using miRNA-based hairpins FREE

A Georgiadis, M Tschernutter, J W B Bainbridge, S J Robbie, J McIntosh, A C Nathwani, A J Smith and R R Ali

Gene Ther 17: 486-493; advance online publication, December 10, 2009; doi:10.1038/gt.2009.162

Restoration of cellular function of mesenchymal stem cells from a hypophosphatasia patient FREE

Y Katsube, N Kotobuki, M Tadokoro, R Kanai, T Taketani, S Yamaguchi and H Ohgushi

Gene Ther 17: 494-502; advance online publication, November 26, 2009; doi:10.1038/gt.2009.156

High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency FREE

E Ayuso, F Mingozzi, J Montane, X Leon, X M Anguela, V Haurigot, S A Edmonson, L Africa, S Zhou, K A High, F Bosch and J F Wright

Gene Ther 17: 503-510; advance online publication, December 3, 2009; doi:10.1038/gt.2009.157

Lentiviral gene ontology (LeGO) vectors equipped with novel drug-selectable fluorescent proteins: new building blocks for cell marking and multi-gene analysis FREE

K Weber, U Mock, B Petrowitz, U Bartsch and B Fehse

Gene Ther 17: 511-520; advance online publication, December 17, 2009; doi:10.1038/gt.2009.149

Neonatal gene transfer using lentiviral vector for murine Pompe disease: long-term expression and glycogen reduction FREE

S O Kyosen, S Iizuka, H Kobayashi, T Kimura, T Fukuda, J Shen, Y Shimada, H Ida, Y Eto and T Ohashi

Gene Ther 17: 521-530; advance online publication, December 24, 2009; doi:10.1038/gt.2009.160

Enhancing DNA vaccine potency by co-administration of xenogenic MHC class-I DNA FREE

T H Kang, J-Y Chung, A Monie, S I Pai, C-F Hung and T-C Wu

Gene Ther 17: 531-540; advance online publication, November 26, 2009; doi:10.1038/gt.2009.152

The SP-C promoter facilitates alveolar type II epithelial cell-specific plasmid nuclear import and gene expression FREE

J V DeGiulio, C D Kaufman and D A Dean

Gene Ther 17: 541-549; advance online publication, January 7, 2010; doi:10.1038/gt.2009.166

TRAIL gene-armed oncolytic poxvirus and oxaliplatin can work synergistically against colorectal cancer FREE

M F Ziauddin, Z S Guo, M E O'Malley, F Austin, P J Popovic, M A Kavanagh, J Li, M Sathaiah, P Thirunavukarasu, B Fang, Y J Lee and D L Bartlett

Gene Ther 17: 550-559; advance online publication, February 25, 2010; doi:10.1038/gt.2010.5

Technical requirements for effective regional hydrodynamic gene delivery to the left lateral lobe of the rat liver FREE

G J Sawyer, X Zhang and J W Fabre

Gene Ther 17: 560-564; advance online publication, January 14, 2010; doi:10.1038/gt.2009.167


Letter to the Editor

Reply to Bridges FREE

D M Kaye, M J Byrne and J M Power

Gene Ther 17: 565-566; advance online publication, December 17, 2009; doi:10.1038/gt.2009.163