TABLE OF CONTENTS

Volume 16, Issue 3 (March 2009)

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News and Commentary

Gene Therapy Trials: lessons and remaining questions

Basic research tries to decrease the risks of translational medicine FREE

M Cavazzana-Calvo

Gene Ther 16: 309-310; doi:10.1038/gt.2009.15

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Review

Tailoring the AAV vector capsid for gene therapy

L H Vandenberghe, J M Wilson and G Gao

Gene Ther 16: 311-319; advance online publication, December 4, 2008; doi:10.1038/gt.2008.170

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Original Articles

A cell penetrating heme oxygenase protein protects heart graft against ischemia/reperfusion injury

J Ma, C K Lau, A Obed, A Dada, A Doenecke, S T Fan, H J Schlitt and T Y Tsui

Gene Ther 16: 320-328; advance online publication, November 6, 2008; doi:10.1038/gt.2008.162

Bacterial delivery of a novel cytolysin to hypoxic areas of solid tumors

R M Ryan, J Green, P J Williams, S Tazzyman, S Hunt, J H Harmey, S C Kehoe and C E Lewis

Gene Ther 16: 329-339; advance online publication, January 29, 2009; doi:10.1038/gt.2008.188

Lentivectors encoding immunosuppressive proteins genetically engineer pancreatic beta-cells to correct diabetes in allogeneic mice

T Kojaoghlanian, A Joseph, A Follenzi, J H Zheng, M Leiser, N Fleischer, M S Horwitz, T P DiLorenzo and H Goldstein

Gene Ther 16: 340-348; advance online publication, December 25, 2008; doi:10.1038/gt.2008.172

Transduction of human neural progenitor cells with foamy virus vectors for differentiation-dependent gene expression

I Rothenaigner, S Kramer, M Meggendorfer, A Rethwilm and R Brack-Werner

Gene Ther 16: 349-358; advance online publication, December 4, 2008; doi:10.1038/gt.2008.173

Role of TLR3 in the immunogenicity of replicon plasmid-based vaccines

S S Diebold, O Schulz, L Alexopoulou, W W Leitner, R A Flavell and C Reis e Sousa

Gene Ther 16: 359-366; advance online publication, December 4, 2008; doi:10.1038/gt.2008.164

An adenoviral vector-based mucosal vaccine is effective in protection against botulism

Q Xu, M E Pichichero, L L Simpson, Md Elias, L A Smith and M Zeng

Gene Ther 16: 367-375; advance online publication, January 8, 2009; doi:10.1038/gt.2008.181

A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients

J-L Li, H-L Liu, X-R Zhang, J-P Xu, W-K Hu, M Liang, S-Y Chen, F Hu and D-T Chu

Gene Ther 16: 376-382; advance online publication, December 25, 2008; doi:10.1038/gt.2008.179

Systemic delivery of IL-10 by an AAV vector prevents vascular remodeling and end-organ damage in stroke-prone spontaneously hypertensive rat

T Nomoto, T Okada, K Shimazaki, T Yoshioka, M Nonaka-Sarukawa, T Ito, K Takeuchi, K-i Katsura, H Mizukami, A Kume, S Ookawara, U Ikeda, Y Katayama and K Ozawa

Gene Ther 16: 383-391; advance online publication, September 25, 2008; doi:10.1038/gt.2008.151

Generation of optimized and urokinase-targeted oncolytic Sendai virus vectors applicable for various human malignancies

H Kinoh, M Inoue, A Komaru, Y Ueda, M Hasegawa and Y Yonemitsu

Gene Ther 16: 392-403; advance online publication, November 27, 2008; doi:10.1038/gt.2008.167

Integration of functional bacterial artificial chromosomes into human cord blood-derived multipotent stem cells

F Zaibak, J Kozlovski, J Vadolas, J P Sarsero, R Williamson and S E Howden

Gene Ther 16: 404-414; advance online publication, January 29, 2009; doi:10.1038/gt.2008.187

Interleukin-6 small interfering RNA improved the herpes simplex virus-induced systemic inflammation in vivo Behcet's disease-like mouse model

J Shim, H O Byun, Y D Lee, E S Lee and S Sohn

Gene Ther 16: 415-425; advance online publication, December 18, 2008; doi:10.1038/gt.2008.180

AAV2/1-TNFR:Fc gene delivery prevents periodontal disease progression

J A Cirelli, C H Park, K MacKool, M Taba Jr, K H Lustig, H Burstein and W V Giannobile

Gene Ther 16: 426-436; advance online publication, December 11, 2008; doi:10.1038/gt.2008.174

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Short Communications

Expression of transgenes in midbrain dopamine neurons using the tyrosine hydroxylase promoter

M S Oh, S J Hong, Y Huh and K-S Kim

Gene Ther 16: 437-440; advance online publication, September 18, 2008; doi:10.1038/gt.2008.148

Identification of the murine firefly luciferase-specific CD8 T-cell epitopes

M P Limberis, C L Bell and J M Wilson

Gene Ther 16: 441-447; advance online publication, January 8, 2009; doi:10.1038/gt.2008.177

Foamy virus as a gene transfer vector to the central nervous system

A V Caprariello, R H Miller and S M Selkirk

Gene Ther 16: 448-452; advance online publication, December 4, 2008; doi:10.1038/gt.2008.171

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