TABLE OF CONTENTS

Volume 16, Issue 1 (January 2009)

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News and Commentary

Cystic fibrosis: Ferreting with fibroblasts for cystic fibrosis FREE

U Griesenbach and E W F W Alton

Gene Ther 16: 1-2; advance online publication, October 2, 2008; doi:10.1038/gt.2008.155

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Review

Progress & Prospects: Gene therapy in aging FREE

S I S Rattan and R Singh

Gene Ther 16: 3-9; advance online publication, November 13, 2008; doi:10.1038/gt.2008.166

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Original Articles

Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization FREE

P Pechan, H Rubin, M Lukason, J Ardinger, E DuFresne, W W Hauswirth, S C Wadsworth and A Scaria

Gene Ther 16: 10-16; advance online publication, July 17, 2008; doi:10.1038/gt.2008.115

Redox proteins thioredoxin 1 and thioredoxin 2 support retinal ganglion cell survival in experimental glaucoma FREE

Y Munemasa, J H Ahn, J M K Kwong, J Caprioli and N Piri

Gene Ther 16: 17-25; advance online publication, August 14, 2008; doi:10.1038/gt.2008.126

Herpes simplex virus vector-mediated delivery of neurturin rescues erectile dysfunction of cavernous nerve injury FREE

R Kato, D Wolfe, C H Coyle, J B Wechuck, P Tyagi, T Tsukamoto, J B Nelson, J C Glorioso, M B Chancellor and N Yoshimura

Gene Ther 16: 26-33; advance online publication, July 31, 2008; doi:10.1038/gt.2008.132

Transplantation of BMSCs expressing hPDGF-A/hBD2 promotes wound healing in rats with combined radiation-wound injury FREE

L Hao, J Wang, Z Zou, G Yan, S Dong, J Deng, X Ran, Y Feng, C Luo, Y Wang and T Cheng

Gene Ther 16: 34-42; advance online publication, August 14, 2008; doi:10.1038/gt.2008.133

A small regulatory element from chromosome 19 enhances liver-specific gene expression FREE

C Li, M Hirsch, P Carter, A Asokan, X Zhou, Z Wu and R J Samulski

Gene Ther 16: 43-51; advance online publication, August 14, 2008; doi:10.1038/gt.2008.134

Gene delivery into ischemic myocardium by double-targeted lipoplexes with anti-myosin antibody and TAT peptide FREE

Y T Ko, W C Hartner, A Kale and V P Torchilin

Gene Ther 16: 52-59; advance online publication, August 14, 2008; doi:10.1038/gt.2008.135

Enhancing transduction of the liver by adeno-associated viral vectors FREE

A C Nathwani, M Cochrane, J McIntosh, C Y C Ng, J Zhou, J T Gray and A M Davidoff

Gene Ther 16: 60-69; advance online publication, August 14, 2008; doi:10.1038/gt.2008.137

Doxycycline-controlled splicing modulation by regulated antisense U7 snRNA expression cassettes FREE

J Marquis, S S Kämpfer, L Angehrn and D Schümperli

Gene Ther 16: 70-77; advance online publication, August 14, 2008; doi:10.1038/gt.2008.138

Microvascular free tissue transfer for gene delivery: in vivo evaluation of different routes of plasmid and adenoviral delivery FREE

V K Agrawal, K M Copeland, Y Barbachano, A Rahim, R Seth, C L White, M Hingorani, C M Nutting, M Kelly, P Harris, H Pandha, A A Melcher, R G Vile, C Porter and K J Harrington

Gene Ther 16: 78-92; advance online publication, September 11, 2008; doi:10.1038/gt.2008.140

Lentiviral gene transfer to reduce atherosclerosis progression by long-term CC-chemokine inhibition FREE

C A Bursill, E McNeill, L Wang, O C Hibbitt, R Wade-Martins, D J Paterson, D R Greaves and K M Channon

Gene Ther 16: 93-102; advance online publication, September 18, 2008; doi:10.1038/gt.2008.141

Extended release of adenovirus from silica implants in vitro and in vivo  FREE

L Kangasniemi, M Koskinen, M Jokinen, M Toriseva, R Ala-Aho, V-M Kähäri, H Jalonen, S Ylä-Herttuala, H Moilanen, U-H Stenman, I Diaconu, A Kanerva, S Pesonen, T Hakkarainen and A Hemminki

Gene Ther 16: 103-110; advance online publication, August 28, 2008; doi:10.1038/gt.2008.142

Transgene optimization significantly improves SIN vector titers, gp91phox expression and reconstitution of superoxide production in X-CGD cells FREE

B Moreno-Carranza, M Gentsch, S Stein, A Schambach, G Santilli, E Rudolf, M F Ryser, S Haria, A J Thrasher, C Baum, S Brenner and M Grez

Gene Ther 16: 111-118; advance online publication, September 11, 2008; doi:10.1038/gt.2008.143

Microwave irradiation enhances gene and oligonucleotide delivery and induces effective exon skipping in myoblasts FREE

T J Doran, P J Lu, G S Vanier, M J Collins, B Wu and Q L Lu

Gene Ther 16: 119-126; advance online publication, September 11, 2008; doi:10.1038/gt.2008.144

Polymeric gene delivery of ischemia-inducible VEGF significantly attenuates infarct size and apoptosis following myocardial infarct FREE

J W Yockman, D Choi, M G Whitten, C W Chang, A Kastenmeier, H Erickson, A Albanil, M Lee, S W Kim and D A Bull

Gene Ther 16: 127-135; advance online publication, September 11, 2008; doi:10.1038/gt.2008.146

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Short Communications

PET imaging of thymidine kinase gene expression in the liver of non-human primates following systemic delivery of an adenoviral vector FREE

A Fontanellas, S Hervas-Stubbs, A Sampedro, M Collantes, A Azpilicueta, I Mauleón, A Pañeda, G Quincoces, J Prieto, I Melero and I Peñuelas

Gene Ther 16: 136-141; advance online publication, July 31, 2008; doi:10.1038/gt.2008.122

Prevention of interferon-stimulated gene expression using microRNA-designed hairpins FREE

M Bauer, N Kinkl, A Meixner, E Kremmer, M Riemenschneider, H Förstl, T Gasser and M Ueffing

Gene Ther 16: 142-147; advance online publication, August 14, 2008; doi:10.1038/gt.2008.123

Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2-/-bold gammac -/-) mouse model FREE

O ter Brake, N Legrand, K J von Eije, M Centlivre, H Spits, K Weijer, B Blom and B Berkhout

Gene Ther 16: 148-153; advance online publication, July 31, 2008; doi:10.1038/gt.2008.124

An efficient transfection method for mouse embryonic stem cells FREE

B S Ko, T C Chang, S K Shyue, Y C Chen and J Y Liou

Gene Ther 16: 154-158; advance online publication, July 31, 2008; doi:10.1038/gt.2008.125

SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors FREE

G Berger, C Goujon, J-L Darlix and A Cimarelli

Gene Ther 16: 159-163; advance online publication, July 31, 2008; doi:10.1038/gt.2008.128

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