Gene Therapy

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Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?

J Weiler, J Hunziker and J Hall

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Figure 1.

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Interference with the miRNA pathway using synthetic oligonucleotides. Inhibition of miRNA activity may be achieved by introducing anti-miRNA oligonucleotides (AMOs) fully complementary to the pri-miRNA, the pre-miRNA or the mature miRNA.

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