Gene Therapy

FIGURE 8

FROM:

Adenovirus-mediated overexpression of a gene prevents hearing loss and progressive inner hair cell loss after transient cochlear ischemia in gerbils

N Hakuba, K Watabe, J Hyodo, T Ohashi, Y Eto, M Taniguchi, L Yang, J Tanaka, R Hata and K Gyo

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Figure 8.

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The rates of inner and outer hair cell loss 11 days after injection of Ad-GDNF vector, Ad-LacZ vector, or artificial perilymph. No cell damage was detected in any group. These results show that at the dose used in this experiment, the virus vector had no toxic effects, even 11 days after virus inoculation.

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