Table 1 - Involvement of various phases of swallowing and other parts of the GI tract in some peripheral neuromuscular disorders
From the following article
Muscle disorders affecting oral and pharyngeal swallowing
Safwan Jaradeh
GI Motility online (2006)
doi:10.1038/gimo35
| Neuromuscular disorder | Oral-phase involvement | Pharyngeal-phase involvement | Esophageal-phase involvement | Other GI manifestations |
|---|---|---|---|---|
| Oculopharyngeal muscular dystrophy | Mild to moderate | Severe | Absent | Absent |
| Myotonic dystrophy | Moderate | Moderate | Moderate | Gallstones, intestinal pseudo-obstruction |
| Duchenne dystrophy | Mild | Moderate | Mild to moderate | Gastric dysmotility and dilatation, intestinal pseudo-obstruction |
| Inflammatory myopathies | Mild to moderate | Moderate to severe | Mild to moderate | Heartburn, nausea/vomiting, diarrhea or constipation, and fecal incontinence |
| Mitochondrial myopathies | Mild | Moderate | Mild | Intestinal pseudo-obstruction, rare |
| Nemaline rod myopathy | Moderate | Moderate | Absent | |
| Myasthenia gravis | Moderate | Moderate | Absent | |
| Lambert-Eaton myasthenic syndrome | Mild | Mild to moderate | Absent | |
| Inflammatory neuropathies | Moderate | Moderate to severe | Absent or mild | |
| Bulbospinal muscular atrophy | Mild | Moderate | Absent | |
| Amyotrophic lateral sclerosis | Moderate | Severe | Absent |
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