Genes and Immunity

FIGURE 2

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Innate immune response gene expression profiles characterize primary antiphospholipid syndrome

I Bernales, A Fullaondo, M J Marín-Vidalled, E Ucar, V Martínez-Taboada, M López-Hoyos and A M Zubiaga

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Figure 2.

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Quantitative real time RT–PCR analysis in samples of primary antiphospholipid syndrome (PAPS), systemic lupus erythematosus (SLE) and thrombosis patients. Gene expression of NCF4, TLR8, CD14, CD163, PLSCR1, TNFSF13, STAT1, G1P2 and OAS2 were analyzed by quantitative RT–PCR in healthy controls (n=17), PAPS patients (n=7), SLE patients (n=12) and thrombosis patients (n=5). In each case, expression values are normalized to the expression of TATA-Box-Binding Protein, used as an internal control. Box-plot components are: box, interquartile range; horizontal line, median; whiskers, 1.5 times interquartile range. Asterisk denotes statistically significant differences between PAPS and any of the other groups (P<0.05, one-way ANOVA simple contrast).

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