Genes and Immunity

TABLE 2

FROM:

Epistatic effects of genes encoding immunoglobulin GM allotypes and interleukin-6 on the production of autoantibodies to 60- and 65-kDa heat-shock proteins

J P Pandey, Z Prohászka, A Veres, G Füst and M Hurme

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Table 2. Anti-Hsp antibody levels according to IL-6 -174 C and GM z carrier status

Genotypes No. Anti-Hsp60 antibody median (IQ range) P Anti-Hsp65 antibody median (IQ range) P
IL-6-174 C/GM z9121.3 (12.3–39.6)0.0026.7 (3.4–15.2)0.038
IL-6-174 C/GM non-z4029.8 (15.7–72.4) 7.9 (3.2–18.4) 
IL-6-174 non-C/ GM z2536.6 (20.8–79.0)a  10.6 (5.2–20.7) 
IL-6-174 non-C/GM non-z1455.6 (25.4–75.4)a  12.4 (9.3–42.5) 

a  P<0.05 as compared to IL-6-174 C/GM z.

 IQ=Interquartile.

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