NPG library
Below is a selection of News and Views, Research Highlights, Reviews, Research Articles, Perspectives and Commentaries published by Nature Publishing group journals on the topic of antivirals. Selected articles on this page are freely available from December 2007 to June 2008.
Letters
RNase H-mediated retrovirus destruction in vivo triggered by oligodeoxynucleotides
Kathrin Matzen, Lina Elzaouk, Alexey A Matskevich, Anja Nitzsche, Jochen Heinrich & Karin Moelling
doi:10.1038/nbt1311
Nature Biotechnology 25, 669-674
An in vitro fluorescence screen to identify antivirals that disrupt hepatitis B virus capsid assembly
Stephen J Stray, Jennifer M Johnson, Benjamin G Kopek & Adam Zlotnick
doi:10.1038/nbt1187
Nature Biotechnology 24, 358-362
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
David V Morrissey, Jennifer A Lockridge, Lucinda Shaw, Karin Blanchard, Kristi Jensen, Wendy Breen, Kimberly Hartsough, Lynn Machemer, Susan Radka, Vasant Jadhav, Narendra Vaish, Shawn Zinnen, Chandra Vargeese, Keith Bowman, Chris S Shaffer, Lloyd B Jeffs, Adam Judge, Ian MacLachlan & Barry Polisky
doi:10.1038/nbt1122
Nature Biotechnology 23, 1002-1007
Perspectives
Out of Africa: what can we learn from HIV-2 about protective immunity to HIV-1?
Sarah L Rowland-Jones & Hilton C Whittle
doi:10.1038/ni0407-329
Nature Immunology 4, 329-331
Future therapies for hepatitis C: where do we go from here?
Samuel Sigal & Ira Jacobson
doi:10.1038/ncpgasthep0736
Nature Clinical Practice Gastroenterology & Hepatology 4, 60-61
Is HIV-1 evolving to a less virulent form in humans?
Kevin K. Ariën, Guido Vanham & Eric J. Arts
doi:10.1038/nrmicro1594
Nature Reviews Microbiology 5, 141-151
Genomics meets HIV-1
Amalio Telenti & David B. Goldstein
doi:10.1038/nrmicro1532
Nature Reviews Microbiology 4, 865-873
Reverse-genetic approaches to the study of Borna disease virus
Juan C. de la Torre
doi:10.1038/nrmicro1489
Nature Reviews Microbiology 4, 777-783
Applying the concepts of financial options to stimulate vaccine development
David Brogan & Elias Mossialos
doi:10.1038/nrd2035
Nature Reviews Drug Discovery 5, 641-647
Selective transmission of CCR5-utilizing HIV-1: the 'gatekeeper' problem resolved?
Leonid Margolis & Robin Shattock
doi:10.1038/nrmicro1387
Nature Reviews Microbiology 4, 312-317
Anti-infective monoclonal antibodies: perils and promise of development
Janice M. Reichert & Matthew C. Dewitz
doi:10.1038/nrd1987
Nature Reviews Drug Discovery 5, 191-195
HIV disease: fallout from a mucosal catastrophe?
Jason M Brenchley, David A Price & Daniel C Douek
doi:10.1038/ni1316
Nature Immunology 7, 235-239
HIV vaccine design: insights from live attenuated SIV vaccines
Wayne C Koff, Philip R Johnson, David I Watkins, Dennis R Burton, Jeffrey D Lifson, Kim J Hasenkrug, Adrian B McDermott, Alan Schultz, Timothy J Zamb, Rosanne Boyle & Ronald C Desrosiers
doi:10.1038/ni1296
Nature Immunology 7, 19-23
Reviews
Mechanisms of Disease: HCV-induced liver injury
John A Mengshol, Lucy Golden-Mason & Hugo R Rosen
doi:10.1038/ncpgasthep0961
Nature Clinical Practice Gastroenterology & Hepatology 4, 622-634
Immunopathology of highly virulent pathogens: insights from Ebola virus
Carisa A Zampieri, Nancy J Sullivan & Gary J Nabel
doi:10.1038/ni1519
Nature Immunology 8, 1159-1164
Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic
Rafi Ahmed, Michael B A Oldstone & Peter Palese
doi:10.1038/ni1530
Nature Immunology 8, 1188-1193
Genetic analysis of resistance to viral infection
Bruce Beutler, Celine Eidenschenk, Karine Crozat, Jean-Luc Imler, Osamu Takeuchi, Jules A. Hoffmann & Shizuo Akira
doi:10.1038/nri2174
Nature Reviews Immunology 7, 753-766
Pathways of clathrin-independent endocytosis
Satyajit Mayor & Richard E. Pagano
doi:10.1038/nrm2216
Nature Reviews Molecular Cell Biology 8, 603-612
Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy
Jan Balzarini
doi:10.1038/nrmicro1707
Nature Reviews Microbiology 5, 583-597
How Ebola and Marburg viruses battle the immune system
Mansour Mohamadzadeh, Lieping Chen & Alan L. Schmaljohn
doi:10.1038/nri2098
Nature Reviews Immunology 7, 556-567
Prospects for a dengue virus vaccine
Stephen S. Whitehead, Joseph E. Blaney, Anna P. Durbin & Brian R. Murphy
doi:10.1038/nrmicro1690
Nature Reviews Microbiology 5, 518-528
Rotavirus vaccines: recent developments and future considerations
Juana Angel, Manuel A. Franco & Harry B. Greenberg
doi:10.1038/nrmicro1692
Nature Reviews Microbiology 5, 529-539
Mapping the future of HIV vaccines
Gary J. Nabel
doi:10.1038/nrmicro1713
Nature Reviews Microbiology 5, 482-484
Replication of hepatitis C virus
Darius Moradpour, François Penin & Charles M. Rice
doi:10.1038/nrmicro1645
Nature Reviews Microbiology 5, 453-463
Host factors exploited by retroviruses
Stephen P. Goff
doi:10.1038/nrmicro1541
Nature Reviews Microbiology 5, 253-263
Virus trafficking – learning from single-virus tracking
Boerries Brandenburg & Xiaowei Zhuang
doi:10.1038/nrmicro1615
Nature Reviews Microbiology 5, 197-208
Experimental approaches to the study of HIV-1 latency
Yefei Han, Megan Wind-Rotolo, Hung-Chih Yang, Janet D. Siliciano & Robert F. Siliciano
doi:10.1038/nrmicro1580
Nature Reviews Microbiology 5, 95-106
Translational control of retroviruses
Laurent Balvay, Marcelo Lopez Lastra, Bruno Sargueil, Jean-Luc Darlix & Théophile Ohlmann
doi:10.1038/nrmicro1599
Nature Reviews Microbiology 5, 128-140
Structural and mechanistic insights into hepatitis C viral translation initiation
Christopher S. Fraser & Jennifer A. Doudna
doi:10.1038/nrmicro1558
Nature Reviews Microbiology 5, 29-38
Antiviral agents active against influenza A viruses
Erik De Clercq
doi:10.1038/nrd2175
Nature Reviews Drug Discovery 5, 1015-1025
Progress and obstacles in the development of an AIDS vaccine
Norman L. Letvin
doi:10.1038/nri1959
Nature Reviews Immunology 6, 930-939
Dendritic-cell interactions with HIV: infection and viral dissemination
Li Wu & Vineet N. KewalRamani
doi:10.1038/nri1960
Nature Reviews Immunology 6, 859-868
Glycan microarray technologies: tools to survey host specificity of influenza viruses
James Stevens, Ola Blixt, James C. Paulson & Ian A. Wilson
doi:10.1038/nrmicro1530
Nature Reviews Microbiology 4, 857-864
MicroRNAs: expression, avoidance and subversion by vertebrate viruses
Peter Sarnow, Catherine L. Jopling, Kara L. Norman, Sylvia Schütz & Karen A. Wehner
doi:10.1038/nrmicro1473
Nature Reviews Microbiology 11, 651-659
Mechanisms of pathogen entry through the endosomal compartments
Jean Gruenberg & F. Gisou van der Goot
doi:10.1038/nrm1959
Nature Reviews Molecular Cell Biology 7, 495-504
Defensins in innate antiviral immunity
Mary E. Klotman & Theresa L. Chang
doi:10.1038/nri1860
Nature Reviews Immunology 6, 447-456
Microbicides and other topical strategies to prevent vaginal transmission of HIV
Michael M. Lederman, Robin E. Offord & Oliver Hartley
doi:10.1038/nri1848
Nature Reviews Immunology 6, 371-382
Parallels among positive-strand RNA viruses, reverse-transcribing viruses and double-stranded RNA viruses
Paul Ahlquist
doi:10.1038/nrmicro1389
Nature Reviews Microbiology 4, 371-382
Influenza and the challenge for immunology
Peter C Doherty, Stephen J Turner, Richard G Webby & Paul G Thomas
doi:10.1038/ni1343
Nature Immunology 7, 449-455
Antiviral antibody responses: the two extremes of a wide spectrum
Lars Hangartner, Rolf M. Zinkernagel & Hans Hengartner
doi:10.1038/nri1783
Nature Reviews Immunology 6, 231-243
Coronavirus infection of the central nervous system: host–virus stand-off
Cornelia C. Bergmann, Thomas E. Lane & Stephen A. Stohlman
doi:10.1038/nrmicro1343
Nature Reviews Microbiology 4, 121-132
Immunopathogenesis of coronavirus infections: implications for SARS
Ajai A. Dandekar & Stanley Perlman
doi:10.1038/nri1732
Nature Reviews Immunology 5, 917-927
Acyclic nucleoside phosphonates: a key class of antiviral drugs
Erik De Clercq & Antonín Holý
doi:10.1038/nrd1877
Nature Reviews Drug Discovery 4, 928-940
Viral and cellular RNA helicases as antiviral targets
Ann D. Kwong, B. Govinda Rao & Kuan-Teh Jeang
doi:10.1038/nrd1853
Nature Reviews Drug Discovery 11, 845-853
