Case Series
Eye (2008) 22, 722–724; doi:10.1038/eye.2008.64; published online 14 March 2008
Optic neuropathy associated with dengue fever
S Sanjay1,2, A M Wagle1,2 and K G Au Eong1,2,3,4,5
- 1Department of Ophthalmology and Visual Sciences, Alexandra Hospital, Singapore, Singapore
- 2Eye Clinic, Jurong Medical Centre, Singapore, Singapore
- 3Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
- 4Singapore Eye Research Institute, Singapore, Singapore
- 5Department of Ophthalmology, Tan Tock Seng Hospital, Singapore, Singapore
Correspondence: S Sanjay, Department of Ophthalmology and Visual Sciences, Alexandra Hospital, 378, Alexandra Road, Singapore 159964. Tel: +65 63793741; Fax: +65 63793618; E-mail: Sanjay_S@alexhosp.com.sg
Received 27 December 2007; Revised 11 February 2008; Accepted 11 February 2008; Published online 14 March 2008.
Abstract
Purpose
To report a case series of three patients of optic neuropathy associated with dengue fever.
Methods
Observational case series.
Results
Three patients aged of 19, 31, and 40 years (cases 1, 2, and 3) complained of unilateral blurring of vision within a week of being diagnosed with dengue fever. Their presenting visual acuities were counting fingers in cases 1 and 2, and 6/6 in case 3, with features suggestive of optic neuropathy. Two of the three patients (cases 2 and 3) had bilateral ocular signs. The visual acuity recovered to 6/9 in case 1, worsened to no light perception in case 2, and remained unchanged in case 3.
Conclusions
Although spontaneous visual recovery is possible, optic neuropathy associated with dengue fever may result in severe and permanent visual loss.
Keywords:
dengue fever, ocular manifestations, optic neuropathy, visual loss
