Clinical Study
Eye (2008) 22, 1469–1475; doi:10.1038/sj.eye.6702925; published online 6 July 2007
Comparison of visual outcomes, photopic contrast sensitivity, wavefront analysis, and patient satisfaction following cataract extraction and IOL implantation: aspheric vs spherical acrylic lenses
Presented in part at the annual meeting of the American Society of Cataract and Refractive Surgery, San Francisco, CA, USA, 17–22 March 2006
H P Sandoval1, L E Fernández de Castro1, D T Vroman1 and K D Solomon1
1Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston, SC, USA
Correspondence: HP Sandoval, Magill Research Center for Vision Correction, MUSC-Storm Eye Institute, 167 Ashley Avenue, Charleston, SC 29425, USA. Tel: 843 792 2305; Fax: 843 792 6347; E-mail: sandoval@musc.edu
Received 14 February 2007; Revised 5 April 2007; Accepted 5 June 2007; Published online 6 July 2007.
Abstract
Purpose
To determine vision quality when testing two acrylic intraocular lenses (IOLs), AcrysofIQ and AcrysofSingle-Piece, after routine cataract extraction and IOL implantation.
Setting
Storm Eye Institute and Magill Research Center for Vision Correction, Medical University of South Carolina, Charleston, SC, USA.
Methods
Prospective, randomized, double-masked study that included 53 eyes of 27 patients who underwent bilateral cataract extraction and IOL implantation. Patients were randomly divided into two groups depending on the type of IOL implanted: AcrysofIQ or AcrysofSingle-Piece. Preoperative, 1- and 3-month postoperative evaluations included ETDRS visual acuity, photopic contrast sensitivity, pupil size, wavefront testing, and a subjective questionnaire. Comparisons between the two groups and comparisons to baseline were made at each visit. P<0.05 was considered statistically significant.
Results
Preoperative, statistically significant differences were evident in response to the subjective questionnaire (near activities, driving dimensions, and overall score) between the two groups. Postoperatively there was a greater increase in contrast sensitivity at 1 and 3 months in the AcrysofIQ group when compared to baseline. Patients with AcrysofIQ IOL had a significant reduction in total high-order aberrations (HOA) and spherical aberration (SA) when compared to those patients with AcrysofSingle-Piece at 1 and 3 months and to baseline. Postoperative patient satisfaction showed no difference among the groups.
Conclusion
The use of a new aspheric acrylic IOL may improve the quality of vision as a result of the reduction of total HOA and SA.
Keywords:
acrylic IOL, aspheric IOL, aberrations, spherical

