Clinical Study
Eye (2006) 20, 810–813. doi:10.1038/sj.eye.6702017; published online 29 July 2005
Effects of sildenafil on blue-on-yellow and white-on-white Humphrey perimetry in 3 months regular use
The authors have no financial interest with any of the material used in this study
S O Dündar1, A Topalo
lu1, M Dündar2 and 
Koçak2
- 1Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, Aydin, Turkey
- 2Department of Urology, Faculty of Medicine, Adnan Menderes University, Aydin, Turkey
Correspondence: SO Dündar, Adnan Menderes University, Tip Fakultesi, Goz Hast. A.D., 09100, Aydin, Turkey. Tel: +90 256 444 12 56; Fax: +90 256 214 64 95; E-mail: orucs@yahoo.com
Received 7 March 2005; Accepted 10 June 2005; Published online 29 July 2005.
Abstract
Purpose
To assess the effects of sildenafil on blue-on-yellow (B/Y) and white-on-white (W/W) Humphrey perimetry in a group of men with erectile dysfunction in 3 months regular use.
Methods
In this prospective study, 14 patients with erectile dysfunction received 50 mg doses of sildenafil (Viagra, Pfizer) two times per week regularly for 3 months. Patients underwent best-corrected visual acuity (BCVA), colour vision, anterior segment and fundus examination, and B/Y and W/W Humphrey perimetry in each eye before and after sildenafil treatment. Changes in mean deviations (MD) were compared separately for both eyes.
Results
No significant changes from baseline were observed in BCVA and colour vision after sildenafil treatment. The anterior segment and fundus examinations revealed no abnormalities. There was no change on B/Y and W/W Humphrey visual field. MD values of B/Y and W/W Humphrey perimetry remained nonsignificant for both eyes after 3 months regular use of sildenafil (P=0.133, and 0.092, respectively, for right, and P=0.221 and 0.925, respectively, for left eyes).
Conclusion
Oral sildenafil used regularly for 3 months produced no effect on B/Y and W/W Humphrey perimetry.
Keywords:
sildenafil, visual field, erectile dysfunction
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