Clinical Study
Eye (2006) 20, 309–314. doi:10.1038/sj.eye.6701867; published online 8 July 2005
To compare argon laser peripheral iridoplasty (ALPI) against systemic medications in treatment of acute primary angle-closure: mid-term results
Financial support: The work described in this paper was substantially supported by a grant from the Research Grants Council of the Hong Kong Special Administrative Region. (Project no. CUHK4090/01M).
Proprietary interest: Nil.
J S M Lai1,2, C C Y Tham2, J K H Chua2, A S Y Poon2, J C H Chan2, S W Lam2 and D S C Lam2
- 1United Christian Hospital, Kowloon, Hong Kong, People's Republic of China
- 2Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, People's Republic of China
Correspondence: JSM Lai, Department of Ophthalmology, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Kowloon, Hong Kong. Tel: +852 23513 3411; Fax: +852 23513 5626; E-mail: laism@ha.org.hk
Received 7 October 2004; Accepted 15 February 2005; Published online 8 July 2005.
Abstract
Purpose
To compare the clinical outcome of argon laser peripheral iridoplasty (ALPI) against systemic medications in treatment of acute primary angle-closure (APAC).
Methods
Consecutive patients with APAC were recruited and randomized to receive one of two treatment options: immediate ALPI or systemic acetazolamide
mannitol. All eyes were followed up for at least 6 months after laser iridotomy. Main outcome measures were intraocular pressure (IOP) and requirement for glaucoma medications.
Results
A total of 41 eyes (39 patients) were randomized into the ALPI group, and 38 eyes (32 patients) into the medical treatment group. There were no significant differences between the two groups in sex, age, presenting IOP, and duration of attack. Mean follow-up durationSD was 15.75.8 months. There were no significant differences between the two groups in mean final IOP and requirement for glaucoma medications.
Conclusions
There were no statistically significant differences in mean IOP and requirement for glaucoma drugs between APAC eyes treated with ALPI and systemic medications.
Keywords:
argon laser peripheral iridoplasty, acute primary angle-closure, medical treatment
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