Clinical Study
Eye (2006) 20, 43–45. doi:10.1038/sj.eye.6701787; published online 15 April 2005
Does lesion size determine the success rate of photodynamic therapy for age-related macular degeneration?
S Sivaprasad1, G M Saleh1 and H Jackson1
1West Kent Eye Centre, Princess Royal University Hospital, Orpington, Kent BR6 8ND, UK
Correspondence: S Sivaprasad, Tel: +44 1689 865784; Fax: +44 1689 863329; E-mail: Senswathi@aol.com
Received 25 August 2004; Revised 13 October 2004; Accepted 13 October 2004; Published online 15 April 2005.
Abstract
Photodynamic therapy (PDT) is a new evidence-based treatment modality available for choroidal neovascularisation (CNV) secondary to age-related macular degeneratin (AMD). Eligibility for PDT is based on the morphological classification of the neovascular complex, the benefit being greater in classic with no occult lesions. Lesion size is also shown to be a predictive factor for treatment benefit. This retrospective case series looked at effect of initial and final lesion size on the visual outcome of patients with subfoveal classic with no occult CNV and found that increasing initial and final lesion size is associated with poorer visual outcome.
Keywords:
age-related macular degeneration, photodynamic therapy, lesion size
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