Clinical Study
Eye (2005) 19, 308–311. doi:10.1038/sj.eye.6701472 Published online 30 July 2004
Inter-device reproducibility of the scanning laser polarimeter with variable cornea compensation
Presented in part at the Association for Research in Vision and Ophthalmology (ARVO) meeting, Fort Lauderdale, Florida, May 2003.
E Z Blumenthal1 and S Frenkel2
- 1Department of Ophthalmology, Hadassah University Hospital, Jerusalem, Israel
- 2Hebrew University-Hadassah Medical School, Jerusalem, Israel
Correspondence: EZ Blumenthal, Tel: +972 2 677 6580; Fax: +972 2 675 8926; E-mail: eblumenthal@md.huji.ac.il
Received 6 July 2003; Accepted 19 January 2004; Published online 30 July 2004.
Abstract
Objective
To evaluate the interdevice reproducibility of retinal nerve fibre layer (RNFL) thickness measurements obtained with the commercially available GDx-VCC, a scanning laser polarimeter with variable (individualized) corneal compensation.
Methods
A prospective instrument validation study in which 13 GDx-VCC devices were tested. One eye each, from three normal subjects were used to test each of the devices, on the same day, by an experienced operator. Variability and reproducibility for each of five GDx parameters were calculated.
Results
For each of five tested GDx parameters, the coefficient of variation and 95% confidence interval range (
m), for the 13 devices, respectively, were: TSNIT avg: 5.1%, 3.84 m; Superior avg: 5.3%, 4.82 m; Inferior avg: 6.1%, 5.50 m; TSNIT standard deviation: 8.6%, 2.92 m; and nerve fibre indicator (NFI): N/A, 5.69. Item reliability (Cronbach's alpha) for the five GDx parameters are: TSNIT-Avg: 0.97, Sup-Avg: 1.00, Inf-Avg: 0.84, TSNIT-SD: 0.99, NFI: 0.99.
Conclusions
With the commercially available GDx-VCC, our results indicate that RNFL measurements appear reproducible across devices.
Keywords:
glaucoma, retinal nerve fibre layer, imaging, scanning laser polarimetry
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