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- The EMBO Journal (2009) 28, 173 - 174
- doi:10.1038/emboj.2008.296
There is an Article (February 2009) associated with this Have you seen ...?.
Neuronal polarity: consolidation for growth, growth for consolidationEMBO Open
Annette Gärtner1 and Carlos G Dotti1
- VIB Department of Molecular and Developmental Genetics, KULeuven—Center for Human Genetics, Leuven, Belgium
Correspondence to:
Carlos G Dotti, Department of Human Genetics, Katholieke Universiteit Leuven, Campus Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium. E-mail: carlos.dotti@med.kuleuven.be
Axonal elongation involves the coordinated assembly and activation of molecular pathways in response to environmental signals. Neurons sense the environment at growth cones to decide on further growth, arborization or consolidation. The work by Ana Mingorance-Le Meur and Timothy P. O'Connor highlights the important role of neurite shaft dynamics in the consolidation process.
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