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Figure 1

A Wingless and Notch double-repression mechanism regulates G1–S transition in the Drosophila wing

Héctor Herranz, Lidia Pérez, Francisco A Martín and Marco Milán

  • The EMBO Journal (2008) 27, 1633 - 1645
  • doi:10.1038/emboj.2008.84

Published online: 1 May 2008

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Wg- and Notch-mediated cell interactions involved in DV boundary formation. (A) Late third instar wing imaginal disc labelled to visualize Wg (green) and Senseless (red) protein expression in boundary and non-boundary cells, respectively. (B) Illustration describing the cell interactions that take place between boundary (white) and non-boundary (black) cells that lead to activation of Notch (N) and expression of Wg and Cut along the DV boundary of the Drosophila wing primordium. N, Notch; Dl, Delta; Ser, Serrate.

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