Table of Contents : The EMBO Journal

Volume 26, Number 4
21 February 2007

pp 915-1197

Environmental fungi or bacteria contaminate the agar plates in the lab and sometimes spoil our experiments. Ignacio L�pez-Go�i (Professor of Microbiology at the University of Navarra, Spain) and Nicol�s L�pez (professional photographer) have captured the marvellous beauty of these undesirable bugs (e-mail :ilgoni@unav.es).

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EMBO Members Review
Top of page
- Human genetics of infectious diseases: a unified theory FREE
  Jean-Laurent Casanova and Laurent Abel
  The EMBO Journal (2007), 26, - 915 - 922, doi:10.1038/sj.emboj.7601558
  Published online: 25 January 2007
  Subject Categories:
  - Immunology | Genomic and Computational Biology
Articles
Top of page
- Monoubiquitylation promotes mitochondrial p53 translocation FREE
  Natasha D Marchenko, Sonja Wolff, Susan Erster, Kerstin Becker and Ute M Moll
  The EMBO Journal (2007), 26, - 923 - 934, doi:10.1038/sj.emboj.7601560
  - Abstract - Monoubiquitylation promotes mitochondrial p53 translocation
  - Full text
  - PDF (263 KB) - Monoubiquitylation promotes mitochondrial p53 translocation
  - Supplementary information
  Published online: 01 February 2007
  Subject Category:
  - Proteins
- Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans FREE
  Nathaniel J Szewczyk, Brant K Peterson, Sami J Barmada, Leah P Parkinson and Lewis A Jacobson
  The EMBO Journal (2007), 26, - 935 - 943, doi:10.1038/sj.emboj.7601540
  - Abstract - Opposed growth factor signals control protein degradation in muscles of : Caenorhabditis elegans
  - Full text
  - PDF (288 KB) - Opposed growth factor signals control protein degradation in muscles of : Caenorhabditis elegans
  Published online: 08 February 2007
  Subject Category:
  - Signal Transduction
- Identification of novel functional TBP-binding sites and general factor repertoires FREE
  Sergey Denissov, Marc van Driel, Renate Voit, Maarten Hekkelman, Tim Hulsen, Nouria Hernandez, Ingrid Grummt, Ron Wehrens and Hendrik Stunnenberg
  The EMBO Journal (2007), 26, - 944 - 954, doi:10.1038/sj.emboj.7601550
  - Abstract - Identification of novel functional TBP-binding sites and general factor repertoires
  - Full text
  - PDF (488 KB) - Identification of novel functional TBP-binding sites and general factor repertoires
  - Supplementary information
  Published online: 01 February 2007
  Subject Category:
  - Chromatin and Transcription
- Region 1.2 of the RNA polymerase subunit controls recognition of the -10 promoter element FREE
  Nikolay Zenkin, Andrey Kulbachinskiy, Yuliya Yuzenkova, Arkady Mustaev, Irina Bass, Konstantin Severinov and Konstantin Brodolin
  The EMBO Journal (2007), 26, - 955 - 964, doi:10.1038/sj.emboj.7601555
  - Abstract - Region 1.2 of the RNA polymerase [sigma] subunit controls recognition of the -10 promoter element
  - Full text
  - PDF (477 KB) - Region 1.2 of the RNA polymerase [sigma] subunit controls recognition of the -10 promoter element
  - Supplementary information
  Published online: 01 February 2007
  Subject Categories:
  - Chromatin and Transcription | Microbiology and Pathogens
- Control of Fur synthesis by the non-coding RNA RyhB and iron-responsive decoding FREE
  Branislav Veerek, Isabella Moll and Udo Bläsi
  The EMBO Journal (2007), 26, - 965 - 975, doi:10.1038/sj.emboj.7601553
  - Abstract - Control of Fur synthesis by the non-coding RNA RyhB and iron-responsive decoding
  - Full text
  - PDF (321 KB) - Control of Fur synthesis by the non-coding RNA RyhB and iron-responsive decoding
  - Supplementary information
  Published online: 01 February 2007
  Subject Category:
  - RNA
- The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2 FREE
  Lauren F Stevenson, Alison Sparks, Nerea Allende-Vega, Dimitris P Xirodimas, David P Lane and Mark K Saville
  The EMBO Journal (2007), 26, - 976 - 986, doi:10.1038/sj.emboj.7601567
  - Abstract - The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2
  - Full text
  - PDF (467 KB) - The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2
  Published online: 08 February 2007
  Subject Category:
  - Proteins
- Impaired DNA damage checkpoint response in MIF-deficient mice FREE
  Alice Nemajerova, Patricio Mena, Gunter Fingerle-Rowson, Ute M Moll and Oleksi Petrenko
  The EMBO Journal (2007), 26, - 987 - 997, doi:10.1038/sj.emboj.7601564
  - Abstract - Impaired DNA damage checkpoint response in MIF-deficient mice
  - Full text
  - PDF (538 KB) - Impaired DNA damage checkpoint response in MIF-deficient mice
  - Supplementary information
  Published online: 08 February 2007
  Subject Categories:
  - Cell Cycle | Molecular Biology of Disease
- Functional interactions of DNA topoisomerases with a human replication origin FREE
  Gulnara Abdurashidova, Sorina Radulescu, Oscar Sandoval, Sotir Zahariev, Miltcho B Danailov, Alexander Demidovich, Laura Santamaria, Giuseppe Biamonti, Silvano Riva and Arturo Falaschi
  The EMBO Journal (2007), 26, - 998 - 1009, doi:10.1038/sj.emboj.7601578
  - Abstract - Functional interactions of DNA topoisomerases with a human replication origin
  - Full text
  - PDF (632 KB) - Functional interactions of DNA topoisomerases with a human replication origin
  - Supplementary information
  Published online: 08 February 2007
  Subject Category:
  - Genome Stability and Dynamics
- XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps FREE
  Jiafeng Gu, Haihui Lu, Brigette Tippin, Noriko Shimazaki, Myron F Goodman and Michael R Lieber
  The EMBO Journal (2007), 26, - 1010 - 1023, doi:10.1038/sj.emboj.7601559
  - Abstract - XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
  - Full text
  - PDF (320 KB) - XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
  - Supplementary information
  Published online: 08 February 2007
  Subject Categories:
  - Genome Stability and Dynamics | Immunology
- Reconstitution and subunit geometry of human condensin complexes FREE
  Itay Onn, Nobuki Aono, Michiko Hirano and Tatsuya Hirano
  The EMBO Journal (2007), 26, - 1024 - 1034, doi:10.1038/sj.emboj.7601562
  - Abstract - Reconstitution and subunit geometry of human condensin complexes
  - Full text
  - PDF (431 KB) - Reconstitution and subunit geometry of human condensin complexes
  - Supplementary information
  Published online: 01 February 2007
  Subject Categories:
  - Chromatin and Transcription | Genome Stability and Dynamics
- Copper homeostasis in Drosophila by complex interplay of import, storage and behavioral avoidance FREE
  Kuppusamy Balamurugan, Dieter Egli, Haiqing Hua, Rama Rajaram, Gerhard Seisenbacher, Oleg Georgiev and Walter Schaffner
  The EMBO Journal (2007), 26, - 1035 - 1044, doi:10.1038/sj.emboj.7601543
  - Abstract - Copper homeostasis in : Drosophila: by complex interplay of import, storage and behavioral avoidance
  - Full text
  - PDF (460 KB) - Copper homeostasis in : Drosophila: by complex interplay of import, storage and behavioral avoidance
  Published online: 08 February 2007
  Subject Category:
  - Development
- Distinct roles for Mediator Cdk8 module subunits in Drosophila development FREE
  Nicolas Loncle, Muriel Boube, Laurent Joulia, Claire Boschiero, Michel Werner, David L Cribbs and Henri-Marc Bourbon
  The EMBO Journal (2007), 26, - 1045 - 1054, doi:10.1038/sj.emboj.7601566
  - Abstract - Distinct roles for Mediator Cdk8 module subunits in : Drosophila: development
  - Full text
  - PDF (464 KB) - Distinct roles for Mediator Cdk8 module subunits in : Drosophila: development
  - Supplementary information
  Published online: 08 February 2007
  Subject Categories:
  - Chromatin and Transcription | Development
- c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis FREE
  Anni I Nieminen, Johanna I Partanen, Annika Hau and Juha Klefstrom
  The EMBO Journal (2007), 26, - 1055 - 1067, doi:10.1038/sj.emboj.7601551
  - Abstract - c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis
  - Full text
  - PDF (680 KB) - c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis
  - Supplementary information
  Published online: 01 February 2007
  Subject Categories:
  - Signal Transduction | Differentiation and Death
- Death effector domain DEDa, a self-cleaved product of caspase-8/Mch5, translocates to the nucleus by binding to ERK1/2 and upregulates procaspase-8 expression via a p53-dependent mechanism FREE
  Zhan Yao, Shanshan Duan, Dezhi Hou, Klaus Heese and Mian Wu
  The EMBO Journal (2007), 26, - 1068 - 1080, doi:10.1038/sj.emboj.7601571
  - Abstract - Death effector domain DEDa, a self-cleaved product of caspase-8/Mch5, translocates to the nucleus by binding to ERK1/2 and upregulates procaspase-8 expression via a p53-dependent mechanism
  - Full text
  - PDF (396 KB) - Death effector domain DEDa, a self-cleaved product of caspase-8/Mch5, translocates to the nucleus by binding to ERK1/2 and upregulates procaspase-8 expression via a p53-dependent mechanism
  - Supplementary information
  Published online: 08 February 2007
  Subject Categories:
  - Signal Transduction | Differentiation and Death
- Distinct C/EBP motifs regulate lipogenic and gluconeogenic gene expression in vivo
  Thomas Å Pedersen, Oxana Bereshchenko, Susana Garcia-Silva, Olga Ermakova, Elke Kurz, Susanne Mandrup, Bo T Porse and Claus Nerlov
  The EMBO Journal (2007), 26, - 1081 - 1093, doi:10.1038/sj.emboj.7601563
  - Abstract - Distinct C/EBP[alpha] motifs regulate lipogenic and gluconeogenic gene expression : in vivo
  - Full text
  - PDF (337 KB) - Distinct C/EBP[alpha] motifs regulate lipogenic and gluconeogenic gene expression : in vivo
  - Supplementary information
  Published online: 08 February 2007
  Subject Categories:
  - Chromatin and Transcription | Cellular Metabolism
- Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania FREE
  Kai Zhang, Justine M Pompey, Fong-Fu Hsu, Phillip Key, Padmavathi Bandhuvula, Julie D Saba, John Turk and Stephen M Beverley
  The EMBO Journal (2007), 26, - 1094 - 1104, doi:10.1038/sj.emboj.7601565
  - Abstract - Redirection of sphingolipid metabolism toward : de novo: synthesis of ethanolamine in : Leishmania
  - Full text
  - PDF (474 KB) - Redirection of sphingolipid metabolism toward : de novo: synthesis of ethanolamine in : Leishmania
  - Supplementary information
  Published online: 08 February 2007
  Subject Categories:
  - Cellular Metabolism | Microbiology and Pathogens
- Role of activation of PIP5K661 by AP-2 complex in synaptic vesicle endocytosis FREE
  Akiko Nakano-Kobayashi, Masakazu Yamazaki, Takamitsu Unoki, Tsunaki Hongu, Chie Murata, Ryo Taguchi, Toshiaki Katada, Michael A Frohman, Takeaki Yokozeki and Yasunori Kanaho
  The EMBO Journal (2007), 26, - 1105 - 1116, doi:10.1038/sj.emboj.7601573
  - Abstract - Role of activation of PIP5K[gamma]661 by AP-2 complex in synaptic vesicle endocytosis
  - Full text
  - PDF (330 KB) - Role of activation of PIP5K[gamma]661 by AP-2 complex in synaptic vesicle endocytosis
  - Supplementary information
  Published online: 08 February 2007
  Subject Categories:
  - Membranes and Transport | Neuroscience
- Postsynaptic chromatin is under neural control at the neuromuscular junction FREE
  Aymeric Ravel-Chapuis, Marie Vandromme, Jean-Luc Thomas and Laurent Schaeffer
  The EMBO Journal (2007), 26, - 1117 - 1128, doi:10.1038/sj.emboj.7601572
  - Abstract - Postsynaptic chromatin is under neural control at the neuromuscular junction
  - Full text
  - PDF (362 KB) - Postsynaptic chromatin is under neural control at the neuromuscular junction
  Published online: 15 February 2007
  Subject Categories:
  - Chromatin and Transcription | Neuroscience
- A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin FREE
  Valeria V Orlova, Eun Young Choi, Changping Xie, Emmanouil Chavakis, Angelika Bierhaus, Eveliina Ihanus, Christie M Ballantyne, Carl G Gahmberg, Marco E Bianchi, Peter P Nawroth and Triantafyllos Chavakis
  The EMBO Journal (2007), 26, - 1129 - 1139, doi:10.1038/sj.emboj.7601552
  - Abstract - A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin
  - Full text
  - PDF (326 KB) - A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin
  - Supplementary information
  Published online: 01 February 2007
  Subject Category:
  - Immunology
- Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca²⁺ signaling in B cells
  Björn Stork, Konstantin Neumann, Ingo Goldbeck, Sebastian Alers, Thilo Kähne, Michael Naumann, Michael Engelke and Jürgen Wienands
  The EMBO Journal (2007), 26, - 1140 - 1149, doi:10.1038/sj.emboj.7601557
  - Abstract - Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca: 2+: signaling in B cells
  - Full text
  - PDF (396 KB) - Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca: 2+: signaling in B cells
  - Supplementary information
  Published online: 08 February 2007
  Subject Categories:
  - Signal Transduction | Immunology
- TGF- induces p65 acetylation to enhance bacteria-induced NF-B activation FREE
  Hajime Ishinaga, Hirofumi Jono, Jae Hyang Lim, Soo-Mi Kweon, Haodong Xu, Un-Hwan Ha, Haidong Xu, Tomoaki Koga, Chen Yan, Xin-Hua Feng, Lin-Feng Chen and Jian-Dong Li
  The EMBO Journal (2007), 26, - 1150 - 1162, doi:10.1038/sj.emboj.7601546
  - Abstract - TGF-[beta] induces p65 acetylation to enhance bacteria-induced NF-[kappa]B activation
  - Full text
  - PDF (351 KB) - TGF-[beta] induces p65 acetylation to enhance bacteria-induced NF-[kappa]B activation
  - Supplementary information
  Published online: 01 February 2007
  Subject Category:
  - Molecular Biology of Disease
- Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles FREE
  Christina J Matheny, Maren E Speck, Patrick R Cushing, Yunpeng Zhou, Takeshi Corpora, Michael Regan, Miki Newman, Liya Roudaia, Caroline L Speck, Ting-Lei Gu, Stephen M Griffey, John H Bushweller and Nancy A Speck
  The EMBO Journal (2007), 26, - 1163 - 1175, doi:10.1038/sj.emboj.7601568
  - Abstract - Disease mutations in : RUNX1: and : RUNX2: create nonfunctional, dominant-negative, or hypomorphic alleles
  - Full text
  - PDF (430 KB) - Disease mutations in : RUNX1: and : RUNX2: create nonfunctional, dominant-negative, or hypomorphic alleles
  - Supplementary information
  Published online: 08 February 2007
  Subject Categories:
  - Molecular Biology of Disease | Structural Biology
- Full-length p40^phox structure suggests a basis for regulation mechanism of its membrane binding FREE
  Kazuya Honbou, Reiko Minakami, Satoru Yuzawa, Ryu Takeya, Nobuo N Suzuki, Sachiko Kamakura, Hideki Sumimoto and Fuyuhiko Inagaki
  The EMBO Journal (2007), 26, - 1176 - 1186, doi:10.1038/sj.emboj.7601561
  - Abstract - Full-length p40: phox: structure suggests a basis for regulation mechanism of its membrane binding
  - Full text
  - PDF (492 KB) - Full-length p40: phox: structure suggests a basis for regulation mechanism of its membrane binding
  Published online: 08 February 2007
  Subject Category:
  - Structural Biology
- Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1 FREE
  Beenu Moza, Ashok K Varma, Rebecca A Buonpane, Penny Zhu, Christine A Herfst, Melissa J Nicholson, Anne-Kathrin Wilbuer, Nilufer P Seth, Kai W Wucherpfennig, John K McCormick, David M Kranz and Eric J Sundberg
  The EMBO Journal (2007), 26, - 1187 - 1197, doi:10.1038/sj.emboj.7601531
  - Abstract - Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1
  - Full text
  - PDF (378 KB) - Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1
  Published online: 01 February 2007
  Subject Categories:
  - Immunology | Structural Biology

Table of Contents

Volume 26, Number 4 21 February 2007

EMBO Members Review

Human genetics of infectious diseases: a unified theory FREE

Subject Categories:

Articles

Monoubiquitylation promotes mitochondrial p53 translocation FREE

Subject Category:

Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans FREE

Subject Category:

Identification of novel functional TBP-binding sites and general factor repertoires FREE

Subject Category:

Region 1.2 of the RNA polymerase subunit controls recognition of the -10 promoter element FREE

Subject Categories:

Control of Fur synthesis by the non-coding RNA RyhB and iron-responsive decoding FREE

Subject Category:

The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2 FREE

Subject Category:

Impaired DNA damage checkpoint response in MIF-deficient mice FREE

Subject Categories:

Functional interactions of DNA topoisomerases with a human replication origin FREE

Subject Category:

XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps FREE

Subject Categories:

Reconstitution and subunit geometry of human condensin complexes FREE

Subject Categories:

Copper homeostasis in Drosophila by complex interplay of import, storage and behavioral avoidance FREE

Subject Category:

Distinct roles for Mediator Cdk8 module subunits in Drosophila development FREE

Subject Categories:

c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis FREE

Subject Categories:

Death effector domain DEDa, a self-cleaved product of caspase-8/Mch5, translocates to the nucleus by binding to ERK1/2 and upregulates procaspase-8 expression via a p53-dependent mechanism FREE

Subject Categories:

Distinct C/EBP motifs regulate lipogenic and gluconeogenic gene expression in vivo

Subject Categories:

Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania FREE

Subject Categories:

Role of activation of PIP5K661 by AP-2 complex in synaptic vesicle endocytosis FREE

Subject Categories:

Postsynaptic chromatin is under neural control at the neuromuscular junction FREE

Subject Categories:

A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin FREE

Subject Category:

Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca2+ signaling in B cells

Subject Categories:

TGF- induces p65 acetylation to enhance bacteria-induced NF-B activation FREE

Subject Category:

Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles FREE

Subject Categories:

Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding FREE

Subject Category:

Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1 FREE

Subject Categories:

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Volume 26, Number 4
21 February 2007

Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca²⁺ signaling in B cells

Full-length p40^phox structure suggests a basis for regulation mechanism of its membrane binding FREE