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The authors and editors assign up to two Subject Categories to each article upon acceptance of the manuscript. Further information   Articles top   Cytosolic factor- and TOM-independent import of C-tail-anchored mitochondrial outer membrane proteins Kiyoko Setoguchi, Hidenori Otera and Katsuyoshi Mihara The EMBO Journal (2006) 25, 5635–5647, doi:10.1038/sj.emboj.7601438 | Abstract | Full text | PDF (780K) | Supplementary Information | Published online: 16 November 2006 Subject Categories: Membranes & Transport GLUT4 is internalized by a cholesterol-dependent nystatin-sensitive mechanism inhibited by insulin Vincent Blot and Timothy E McGraw The EMBO Journal (2006) 25, 5648–5658, doi:10.1038/sj.emboj.7601462 | Abstract | Full text | PDF (442K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Membranes & Transport | Signal Transduction The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels Tomasz Wegierski, Kerstin Hill, Michael Schaefer and Gerd Walz The EMBO Journal (2006) 25, 5659–5669, doi:10.1038/sj.emboj.7601429 | Abstract | Full text | PDF (620K) | Supplementary Information | Published online: 16 November 2006 Subject Categories: Membranes & Transport | Proteins GSK-3-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome Katsumi Fumoto, Casper C Hoogenraad and Akira Kikuchi The EMBO Journal (2006) 25, 5670–5682, doi:10.1038/sj.emboj.7601459 | Abstract | Full text | PDF (535K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Cell & Tissue Architecture p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration Mark R Frey, Rebecca S Dise, Karen L Edelblum and D Brent Polk The EMBO Journal (2006) 25, 5683–5692, doi:10.1038/sj.emboj.7601457 | Abstract | Full text | PDF (304K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Signal Transduction Asymmetric conformational changes in a GPCR dimer controlled by G-proteins Marjorie Damian, Aimée Martin, Danielle Mesnier, Jean-Philippe Pin and Jean-Louis Banères The EMBO Journal (2006) 25, 5693–5702, doi:10.1038/sj.emboj.7601449 | Abstract | Full text | PDF (300K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Signal Transduction p53 mediates the negative regulation of MDM2 by orphan receptor TR3 Bi-xing Zhao, Hang-zi Chen, Na-zi Lei, Gui-deng Li, Wen-xiu Zhao, Yan-yan Zhan, Bo Liu, Sheng-cai Lin and Qiao Wu The EMBO Journal (2006) 25, 5703–5715, doi:10.1038/sj.emboj.7601435 | Abstract | Full text | PDF (582K) | Published online: 30 November 2006 Subject Categories: Signal Transduction | Proteins Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation Seung Jin Han, Sergio Vaccari, Taku Nedachi, Carsten B Andersen, Kristina S Kovacina, Richard A Roth and Marco Conti The EMBO Journal (2006) 25, 5716–5725, doi:10.1038/sj.emboj.7601431 | Abstract | Full text | PDF (389K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Signal Transduction | Cell Cycle Repression of ADH1 and ADH3 during zinc deficiency by Zap1-induced intergenic RNA transcripts Amanda J Bird, Mat Gordon, David J Eide and Dennis R Winge The EMBO Journal (2006) 25, 5726–5734, doi:10.1038/sj.emboj.7601453 | Abstract | Full text | PDF (436K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Chromatin & Transcription NoRC-dependent nucleosome positioning silences rRNA genes Junwei Li, Gernot Längst and Ingrid Grummt The EMBO Journal (2006) 25, 5735–5741, doi:10.1038/sj.emboj.7601454 | Abstract | Full text | PDF (170K) | Published online: 30 November 2006 Subject Categories: Chromatin & Transcription hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37 Xiao-Bo Qiu, Song-Ying Ouyang, Chao-Jun Li, Shiying Miao, Linfang Wang and Alfred L Goldberg The EMBO Journal (2006) 25, 5742–5753, doi:10.1038/sj.emboj.7601450 | Abstract | Full text | PDF (266K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Proteins RecFOR proteins are essential for Pol V-mediated translesion synthesis and mutagenesis Shingo Fujii, Asako Isogawa and Robert P Fuchs The EMBO Journal (2006) 25, 5754–5763, doi:10.1038/sj.emboj.7601474 | Abstract | Full text | PDF (528K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Genome Stability & Dynamics A Cdt1–geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus Malik Lutzmann, Domenico Maiorano and Marcel Méchali The EMBO Journal (2006) 25, 5764–5774, doi:10.1038/sj.emboj.7601436 | Abstract | Full text | PDF (272K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Genome Stability & Dynamics ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling Thomas Stiff, Sarah A Walker, Karen Cerosaletti, Aaron A Goodarzi, Eva Petermann, Pat Concannon, Mark O'Driscoll and Penny A Jeggo The EMBO Journal (2006) 25, 5775–5782, doi:10.1038/sj.emboj.7601446 | Abstract | Full text | PDF (343K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Genome Stability & Dynamics Drosophila homologs of mammalian TNF/TNFR-related molecules regulate segregation of Miranda/Prospero in neuroblasts Huashan Wang, Yu Cai, William Chia and Xiaohang Yang The EMBO Journal (2006) 25, 5783–5793, doi:10.1038/sj.emboj.7601461 | Abstract | Full text | PDF (629K) | Published online: 30 November 2006 Subject Categories: Development Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans Kiyokazu Morita and Min Han The EMBO Journal (2006) 25, 5794–5804, doi:10.1038/sj.emboj.7601451 | Abstract | Full text | PDF (315K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Development c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3 Kate D Sutherland, François Vaillant, Warren S Alexander, Tim M Wintermantel, Natasha C Forrest, Sheridan L Holroyd, Edward J McManus, Gunther Schutz, Christine J Watson, Lewis A Chodosh, Geoffrey J Lindeman and Jane E Visvader The EMBO Journal (2006) 25, 5805–5815, doi:10.1038/sj.emboj.7601455 | Abstract | Full text | PDF (645K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Signal Transduction | Development Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells Nadège Vernet, Christine Dennefeld, Florian Guillou, Pierre Chambon, Norbert B Ghyselinck and Manuel Mark The EMBO Journal (2006) 25, 5816–5825, doi:10.1038/sj.emboj.7601447 | Abstract | Full text | PDF (698K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Signal Transduction | Development TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration Mahasweta Girgenrath, Shawn Weng, Christine A Kostek, Beth Browning, Monica Wang, Sharron AN Brown, Jeffrey A Winkles, Jennifer S Michaelson, Norm Allaire, Pascal Schneider, Martin L Scott, Yen-ming Hsu, Hideo Yagita, Richard A Flavell, Jeffrey Boone Miller, Linda C Burkly and Timothy S Zheng The EMBO Journal (2006) 25, 5826–5839, doi:10.1038/sj.emboj.7601441 | Abstract | Full text | PDF (626K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Signal Transduction | Differentiation & Death Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast–osteoblast coupling Jiyoon Ryu, Hyung Joon Kim, Eun-Ju Chang, Hao Huang, Yoshiko Banno and Hong-Hee Kim The EMBO Journal (2006) 25, 5840–5851, doi:10.1038/sj.emboj.7601430 | Abstract | Full text | PDF (633K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Signal Transduction | Differentiation & Death Redundant functions of RIM1 and RIM2 in Ca2+-triggered neurotransmitter release Susanne Schoch, Tobias Mittelstaedt, Pascal S Kaeser, Daniel Padgett, Nicole Feldmann, Vivien Chevaleyre, Pablo E Castillo, Robert E Hammer, Weiping Han, Frank Schmitz, Weichun Lin and Thomas C Südhof The EMBO Journal (2006) 25, 5852–5863, doi:10.1038/sj.emboj.7601425 | Abstract | Full text | PDF (477K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Neuroscience AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K+ channels into open leak channels Guillaume Sandoz, Susanne Thümmler, Fabrice Duprat, Sylvain Feliciangeli, Joëlle Vinh, Pierre Escoubas, Nicolas Guy, Michel Lazdunski and Florian Lesage The EMBO Journal (2006) 25, 5864–5872, doi:10.1038/sj.emboj.7601437 | Abstract | Full text | PDF (381K) | Supplementary Information | Published online: 16 November 2006 Subject Categories: Membranes & Transport | Neuroscience CaMKII translocation requires local NMDA receptor-mediated Ca2+ signaling Agnes Thalhammer, York Rudhard, Cezar M Tigaret, Kirill E Volynski, Dmitri A Rusakov and Ralf Schoepfer The EMBO Journal (2006) 25, 5873–5883, doi:10.1038/sj.emboj.7601420 | Abstract | Full text | PDF (562K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Signal Transduction | Neuroscience The G12-RGS RhoGEF-RhoA signalling pathway regulates neurotransmitter release in C. elegans Emma Hiley, Rachel McMullan and Stephen J Nurrish The EMBO Journal (2006) 25, 5884–5895, doi:10.1038/sj.emboj.7601458 | Abstract | Full text | PDF (661K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Signal Transduction | Neuroscience Huntingtin inhibits caspase-3 activation Yu Zhang, Blair R Leavitt, Jeremy M van Raamsdonk, Ioannis Dragatsis, Dan Goldowitz, Marcy E MacDonald, Michael R Hayden and Robert M Friedlander The EMBO Journal (2006) 25, 5896–5906, doi:10.1038/sj.emboj.7601445 | Abstract | Full text | PDF (606K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Neuroscience | Molecular Biology of Disease ATAB2 is a novel factor in the signalling pathway of light-controlled synthesis of photosystem proteins Frédy Barneche, Veronika Winter, Michèle Crèvecur and Jean-David Rochaix The EMBO Journal (2006) 25, 5907–5918, doi:10.1038/sj.emboj.7601472 | Abstract | Full text | PDF (655K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Proteins | Plant Biology DNA segregation by the bacterial actin AlfA during Bacillus subtilis growth and development Eric Becker, Nick C Herrera, Felizza Q Gunderson, Alan I Derman, Amber L Dance, Jennifer Sims, Rachel A Larsen and Joe Pogliano The EMBO Journal (2006) 25, 5919–5931, doi:10.1038/sj.emboj.7601443 | Abstract | Full text | PDF (443K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Microbiology & Pathogens Identification of a strong binding site for kinesin on the microtubule using mutant analysis of tubulin Seiichi Uchimura, Yusuke Oguchi, Miho Katsuki, Takeo Usui, Hiroyuki Osada, Jun-ichi Nikawa, Shin'ichi Ishiwata and Etsuko Muto The EMBO Journal (2006) 25, 5932–5941, doi:10.1038/sj.emboj.7601442 | Abstract | Full text | PDF (410K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Membranes & Transport | Structural Biology Crystal structures of leucyl/phenylalanyl-tRNA-protein transferase and its complex with an aminoacyl-tRNA analog Kyoko Suto, Yoshihiro Shimizu, Kazunori Watanabe, Takuya Ueda, Shuya Fukai, Osamu Nureki and Kozo Tomita The EMBO Journal (2006) 25, 5942–5950, doi:10.1038/sj.emboj.7601433 | Abstract | Full text | PDF (438K) | Supplementary Information | Published online: 16 November 2006 Subject Categories: RNA | Proteins X-ray structure of the membrane-bound cytochrome c quinol dehydrogenase NrfH reveals novel haem coordination Maria Luisa Rodrigues, Tânia F Oliveira, Inês A C Pereira and Margarida Archer The EMBO Journal (2006) 25, 5951–5960, doi:10.1038/sj.emboj.7601439 | Abstract | Full text | PDF (461K) | Published online: 30 November 2006 Subject Categories: Proteins | Structural Biology Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA Elena Bochkareva, Dariusz Martynowski, Almagoul Seitova and Alexey Bochkarev The EMBO Journal (2006) 25, 5961–5969, doi:10.1038/sj.emboj.7601452 | Abstract | Full text | PDF (422K) | Supplementary Information | Published online: 30 November 2006 Subject Categories: Genome Stability & Dynamics | Structural Biology Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase Chien-Hua Pai, Bing-Yu Chiang, Tzu- Ping Ko, Chia-Cheng Chou, Cheong-Meng Chong, Fang-Jiun Yen, Shoujun Chen, James K Coward, Andrew H-J Wang and Chun-Hung Lin The EMBO Journal (2006) 25, 5970–5982, doi:10.1038/sj.emboj.7601440 | Abstract | Full text | PDF (731K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Microbiology & Pathogens | Structural Biology A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain -ketoacid dehydrogenase complex Masato Kato, R Max Wynn, Jacinta L Chuang, Chad A Brautigam, Myra Custorio and David T Chuang The EMBO Journal (2006) 25, 5983–5994, doi:10.1038/sj.emboj.7601444 | Abstract | Full text | PDF (4018K) | Supplementary Information | Published online: 23 November 2006 Subject Categories: Molecular Biology of Disease | Structural Biology

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