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The EMBO Journal (2006) 25, 312–322, doi:10.1038/sj.emboj.7600940 Published online 12 January 2006 |
| Figure 3 |
| Antagonistic sensory cues generate gustatory plasticity in Caenorhabditis elegans |
| Renate K Hukema, Suzanne Rademakers, Martijn P J Dekkers, Jan Burghoorn and Gert Jansen |
subunits GPA-1 and ODR-3 modulate gustatory plasticity. (A) GPA-1 is involved in gustatory plasticity (P<0.0001) and functions in the same genetic pathway as GPC-1, since gpa-1 gpc-1 animals showed the same response as the single mutants (P>0.05). (B) Also, ODR-3 is involved in gustatory plasticity (P<0.0001). Avoidance after pre-exposure could be restored by expressing ODR-3 in the ADF neurons (P<0.0001), but not by expressing it in the ASH neurons (P>0.05). (C) ODR-3 signalling mediates avoidance of 1 M NaCl (P<0.0001). Avoidance could be restored by expressing ODR-3 in the ASH neurons (P<0.0001), but not by expressing it in the ADF neurons (P>0.05).
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