Table of Contents

Volume 24, Number 6
23 March 2005
pp 1095-1301
Male Proboscis Monkey (Nasalis larvatus) � The proboscis monkey is a relatively large monkey species with a pot belly and a big nose. In Borneo, it is known as 'orang belanda', which is Malay for 'Dutchman'. This endangered species is confined to the mangrove swamps in Borneo and is under threat of losing its habitat as more land is cleared for commercial tree species. The pot belly is a 'fermentation tank' as the species eats fibrous fruits and leaves. The fleshy nose is more prominent in males and seems to be a secondary sexual characteristic. Proboscis monkeys are difficult to raise in zoos in temperate countries and are therefore seldom seen outside tropical regions. This male was photographed in April 2004 in the Labuk Bay Sanctuary in Sabah, Malaysia, a private initiative that has preserved a fragment of coastal mangroves. The image was captured with a Canon EOS1 DII, 500 mm f4 lens, iso 400, 1/200, f11. The photographer, Graeme Guy, runs a Signal Transduction Laboratory at the Institute of Molecular and Cell Biology, which is situated at Biopolis, a new biomedical hub funded by A-Star, a Singapore Government sponsored agency.
Medal Review
Top of pageMice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging
The EMBO Journal (2005), 24, - 1095 - 1103, doi:10.1038/sj.emboj.7600598
- Abstract - Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging
- Full text
- PDF (499 KB) - Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging
Published online: 10 March 2005
Subject Categories:
Boveri revisited FREE
The EMBO Journal (2005), 24, - 1104 - 1110, doi:10.1038/sj.emboj.7600583
Published online: 10 March 2005
Subject Categories:
Articles
Top of pageStructure and biochemical analysis of a secretin pilot protein FREE
The EMBO Journal (2005), 24, - 1111 - 1121, doi:10.1038/sj.emboj.7600610
- Abstract - Structure and biochemical analysis of a secretin pilot protein
- Full text
- PDF (507 KB) - Structure and biochemical analysis of a secretin pilot protein
Published online: 10 March 2005
Subject Categories:
-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking
The EMBO Journal (2005), 24, - 1122 - 1133, doi:10.1038/sj.emboj.7600600
- Abstract - [gamma]-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking
- Full text
- PDF (645 KB) - [gamma]-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking
- Supplementary information
Published online: 10 March 2005
Subject Category:
p38
regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP
FREE The EMBO Journal (2005), 24, - 1134 - 1145, doi:10.1038/sj.emboj.7600578
- Abstract - p38[gamma] regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP
- Full text
- PDF (344 KB) - p38[gamma] regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP
- Supplementary information
Published online: 24 February 2005
Subject Categories:
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions FREE
The EMBO Journal (2005), 24, - 1146 - 1156, doi:10.1038/sj.emboj.7600605
- Abstract - E-cadherin is essential for : in vivo: epidermal barrier function by regulating tight junctions
- Full text
- PDF (653 KB) - E-cadherin is essential for : in vivo: epidermal barrier function by regulating tight junctions
- Supplementary information
Published online: 03 March 2005
Subject Categories:
Regulation of NF-
B and p53 through activation of ATR and Chk1 by the ARF tumour suppressor
FREE The EMBO Journal (2005), 24, - 1157 - 1169, doi:10.1038/sj.emboj.7600608
- Abstract - Regulation of NF-[kappa]B and p53 through activation of ATR and Chk1 by the ARF tumour suppressor
- Full text
- PDF (433 KB) - Regulation of NF-[kappa]B and p53 through activation of ATR and Chk1 by the ARF tumour suppressor
- Supplementary information
Published online: 10 March 2005
Subject Categories:
RhoE function is regulated by ROCK I-mediated phosphorylation FREE
The EMBO Journal (2005), 24, - 1170 - 1180, doi:10.1038/sj.emboj.7600612
- Abstract - RhoE function is regulated by ROCK I-mediated phosphorylation
- Full text
- PDF (491 KB) - RhoE function is regulated by ROCK I-mediated phosphorylation
Published online: 03 March 2005
Subject Categories:
Noncanonical Wnt-4 signaling and EAF2 are required for eye development in Xenopus laevis FREE
The EMBO Journal (2005), 24, - 1181 - 1191, doi:10.1038/sj.emboj.7600603
- Abstract - Noncanonical Wnt-4 signaling and EAF2 are required for eye development in : Xenopus laevis
- Full text
- PDF (548 KB) - Noncanonical Wnt-4 signaling and EAF2 are required for eye development in : Xenopus laevis
- Supplementary information
Published online: 10 March 2005
Subject Categories:
The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase FREE
The EMBO Journal (2005), 24, - 1192 - 1201, doi:10.1038/sj.emboj.7600584
- Abstract - The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase
- Full text
- PDF (349 KB) - The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase
Published online: 24 February 2005
Subject Categories:
LdpA: a component of the circadian clock senses redox state of the cell FREE
The EMBO Journal (2005), 24, - 1202 - 1210, doi:10.1038/sj.emboj.7600606
- Abstract - LdpA: a component of the circadian clock senses redox state of the cell
- Full text
- PDF (259 KB) - LdpA: a component of the circadian clock senses redox state of the cell
- Supplementary information
Published online: 10 March 2005
Subject Categories:
Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication FREE
The EMBO Journal (2005), 24, - 1211 - 1221, doi:10.1038/sj.emboj.7600597
- Abstract - Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication
- Full text
- PDF (319 KB) - Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication
- Supplementary information
Published online: 03 March 2005
Subject Categories:
Histone trimethylation by Set1 is coordinated by the RRM, autoinhibitory, and catalytic domains
The EMBO Journal (2005), 24, - 1222 - 1231, doi:10.1038/sj.emboj.7600607
- Abstract - Histone trimethylation by Set1 is coordinated by the RRM, autoinhibitory, and catalytic domains
- Full text
- PDF (473 KB) - Histone trimethylation by Set1 is coordinated by the RRM, autoinhibitory, and catalytic domains
- Supplementary information
Published online: 03 March 2005
Subject Category:
Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells FREE
The EMBO Journal (2005), 24, - 1232 - 1242, doi:10.1038/sj.emboj.7600593
- Abstract - Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells
- Full text
- PDF (298 KB) - Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells
- Supplementary information
Published online: 24 February 2005
Subject Categories:
TRB3, a novel ER stress-inducible gene, is induced via ATF4–CHOP pathway and is involved in cell death FREE
The EMBO Journal (2005), 24, - 1243 - 1255, doi:10.1038/sj.emboj.7600596
- Abstract - TRB3: , a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
- Full text
- PDF (301 KB) - TRB3: , a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
- Supplementary information
Published online: 10 March 2005
Subject Categories:
CaMKII
-mediated inactivation of the Kin I kinesin MCAK is essential for bipolar spindle formation
FREE The EMBO Journal (2005), 24, - 1256 - 1266, doi:10.1038/sj.emboj.7600601
- Abstract - CaMKII[gamma]-mediated inactivation of the Kin I kinesin MCAK is essential for bipolar spindle formation
- Full text
- PDF (508 KB) - CaMKII[gamma]-mediated inactivation of the Kin I kinesin MCAK is essential for bipolar spindle formation
- Supplementary information
Published online: 03 March 2005
Subject Category:
Impairment of replication fork progression mediates RNA polII transcription-associated recombination FREE
The EMBO Journal (2005), 24, - 1267 - 1276, doi:10.1038/sj.emboj.7600602
- Abstract - Impairment of replication fork progression mediates RNA polII transcription-associated recombination
- Full text
- PDF (357 KB) - Impairment of replication fork progression mediates RNA polII transcription-associated recombination
Published online: 03 March 2005
Subject Category:
Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments FREE
The EMBO Journal (2005), 24, - 1277 - 1286, doi:10.1038/sj.emboj.7600594
- Abstract - Dectin-1 mediates macrophage recognition of : Candida albicans: yeast but not filaments
- Full text
- PDF (355 KB) - Dectin-1 mediates macrophage recognition of : Candida albicans: yeast but not filaments
- Supplementary information
Published online: 24 February 2005
Subject Categories:
Listeria monocytogenes exploits ERM protein functions to efficiently spread from cell to cell
The EMBO Journal (2005), 24, - 1287 - 1300, doi:10.1038/sj.emboj.7600595
- Abstract - Listeria monocytogenes: exploits ERM protein functions to efficiently spread from cell to cell
- Full text
- PDF (772 KB) - Listeria monocytogenes: exploits ERM protein functions to efficiently spread from cell to cell
- Supplementary information
Published online: 24 February 2005
Subject Categories:
Corrigendum
Top of pagePACS-2 controls endoplasmic reticulum–mitochondria communication and Bid-mediated apoptosis FREE
The EMBO Journal (2005), 24, - 1301, doi:10.1038/sj.emboj.7600637



