Table of Contents
Volume 24, Number 2
26 January 2005
pp 229-437
Horseshoe crab (Carcinoscorpius rotundicauda): a "living fossil" harbouring the ancient origin of the complement system � the background shows haemocytes which, together with the plasma proteins, are highly immune-responsive in mounting an immediate innate immune defense against pathogen infection. The image was provided by Jeak Ling Ding, PhD, a professor at the National University of Singapore, with assistance from Ms Ann Nee Yong. Please see the article by Zhu et al on page 382 of this issue of The EMBO Journal for details.
Articles
Top of pageFunctional analysis of a structural model of the ATP-binding site of the KATP channel Kir6.2 subunit FREE
The EMBO Journal (2005), 24, - 229 - 239, doi:10.1038/sj.emboj.7600487
- Abstract - Functional analysis of a structural model of the ATP-binding site of the K: ATP: channel Kir6.2 subunit
- Full text
- PDF (587 KB) - Functional analysis of a structural model of the ATP-binding site of the K: ATP: channel Kir6.2 subunit
Published online: 13 January 2005
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Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53 FREE
The EMBO Journal (2005), 24, - 240 - 250, doi:10.1038/sj.emboj.7600535
- Abstract - Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53
- Full text
- PDF (557 KB) - Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53
Published online: 06 January 2005
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X-ray crystallography study on ribosome recycling: the mechanism of binding and action of RRF on the 50S ribosomal subunit FREE
The EMBO Journal (2005), 24, - 251 - 260, doi:10.1038/sj.emboj.7600525
- Abstract - X-ray crystallography study on ribosome recycling: the mechanism of binding and action of RRF on the 50S ribosomal subunit
- Full text
- PDF (561 KB) - X-ray crystallography study on ribosome recycling: the mechanism of binding and action of RRF on the 50S ribosomal subunit
- Supplementary information
Published online: 23 December 2004
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Structural insights into the EB1–APC interaction FREE
The EMBO Journal (2005), 24, - 261 - 269, doi:10.1038/sj.emboj.7600529
- Abstract - Structural insights into the EB1-APC interaction
- Full text
- PDF (323 KB) - Structural insights into the EB1-APC interaction
- Supplementary information
Published online: 23 December 2004
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Bacterial chromosome segregation: structure and DNA binding of the Soj dimer — a conserved biological switch FREE
The EMBO Journal (2005), 24, - 270 - 282, doi:10.1038/sj.emboj.7600530
- Abstract - Bacterial chromosome segregation: structure and DNA binding of the Soj dimer [mdash] a conserved biological switch
- Full text
- PDF (720 KB) - Bacterial chromosome segregation: structure and DNA binding of the Soj dimer [mdash] a conserved biological switch
Published online: 06 January 2005
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Escherichia coli dihydroxyacetone kinase controls gene expression by binding to transcription factor DhaR FREE
The EMBO Journal (2005), 24, - 283 - 293, doi:10.1038/sj.emboj.7600517
- Abstract - Escherichia coli: dihydroxyacetone kinase controls gene expression by binding to transcription factor DhaR
- Full text
- PDF (513 KB) - Escherichia coli: dihydroxyacetone kinase controls gene expression by binding to transcription factor DhaR
- Supplementary information
Published online: 16 December 2004
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Bidirectional signals transduced by DAPK–ERK interaction promote the apoptotic effect of DAPK FREE
The EMBO Journal (2005), 24, - 294 - 304, doi:10.1038/sj.emboj.7600510
- Abstract - Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK
- Full text
- PDF (562 KB) - Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK
- Supplementary information
Published online: 16 December 2004
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Tyrosine phosphatase SHP-2 is a mediator of activity-dependent neuronal excitotoxicity
The EMBO Journal (2005), 24, - 305 - 314, doi:10.1038/sj.emboj.7600522
- Abstract - Tyrosine phosphatase SHP-2 is a mediator of activity-dependent neuronal excitotoxicity
- Full text
- PDF (263 KB) - Tyrosine phosphatase SHP-2 is a mediator of activity-dependent neuronal excitotoxicity
- Supplementary information
Published online: 13 January 2005
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Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception FREE
The EMBO Journal (2005), 24, - 315 - 324, doi:10.1038/sj.emboj.7600515
- Abstract - Silencing of the Ca: v: 3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception
- Full text
- PDF (314 KB) - Silencing of the Ca: v: 3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception
- Supplementary information
Published online: 16 December 2004
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Identification of neuromedin S and its possible role in the mammalian circadian oscillator system FREE
The EMBO Journal (2005), 24, - 325 - 335, doi:10.1038/sj.emboj.7600526
- Abstract - Identification of neuromedin S and its possible role in the mammalian circadian oscillator system
- Full text
- PDF (345 KB) - Identification of neuromedin S and its possible role in the mammalian circadian oscillator system
- Supplementary information
Published online: 06 January 2005
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Myc represses transcription through recruitment of DNA methyltransferase corepressor FREE
The EMBO Journal (2005), 24, - 336 - 346, doi:10.1038/sj.emboj.7600509
- Abstract - Myc represses transcription through recruitment of DNA methyltransferase corepressor
- Full text
- PDF (241 KB) - Myc represses transcription through recruitment of DNA methyltransferase corepressor
- Supplementary information
Published online: 16 December 2004
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Histone modifications defining active genes persist after transcriptional and mitotic inactivation
The EMBO Journal (2005), 24, - 347 - 357, doi:10.1038/sj.emboj.7600516
- Abstract - Histone modifications defining active genes persist after transcriptional and mitotic inactivation
- Full text
- PDF (448 KB) - Histone modifications defining active genes persist after transcriptional and mitotic inactivation
- Supplementary information
Published online: 16 December 2004
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Inducible DNA-loop formation blocks transcriptional activation by an SV40 enhancer FREE
The EMBO Journal (2005), 24, - 358 - 367, doi:10.1038/sj.emboj.7600531
- Abstract - Inducible DNA-loop formation blocks transcriptional activation by an SV40 enhancer
- Full text
- PDF (380 KB) - Inducible DNA-loop formation blocks transcriptional activation by an SV40 enhancer
- Supplementary information
Published online: 13 January 2005
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Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease
The EMBO Journal (2005), 24, - 368 - 381, doi:10.1038/sj.emboj.7600521
- Abstract - Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease
- Full text
- PDF (621 KB) - Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease
- Supplementary information
Published online: 06 January 2005
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The ancient origin of the complement system FREE
The EMBO Journal (2005), 24, - 382 - 394, doi:10.1038/sj.emboj.7600533
- Abstract - The ancient origin of the complement system
- Full text
- PDF (1,023 KB) - The ancient origin of the complement system
- Supplementary information
Published online: 23 December 2004
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Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus FREE
The EMBO Journal (2005), 24, - 395 - 404, doi:10.1038/sj.emboj.7600520
- Abstract - Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in : Xenopus
- Full text
- PDF (377 KB) - Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in : Xenopus
Published online: 16 December 2004
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Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance FREE
The EMBO Journal (2005), 24, - 405 - 417, doi:10.1038/sj.emboj.7600511
- Abstract - Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance
- Full text
- PDF (602 KB) - Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance
- Supplementary information
Published online: 23 December 2004
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Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM FREE
The EMBO Journal (2005), 24, - 418 - 427, doi:10.1038/sj.emboj.7600534
- Abstract - Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM
- Full text
- PDF (302 KB) - Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM
- Supplementary information
Published online: 23 December 2004
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The VirE3 protein of Agrobacterium mimics a host cell function required for plant genetic transformation FREE
The EMBO Journal (2005), 24, - 428 - 437, doi:10.1038/sj.emboj.7600524
- Abstract - The VirE3 protein of : Agrobacterium: mimics a host cell function required for plant genetic transformation
- Full text
- PDF (318 KB) - The VirE3 protein of : Agrobacterium: mimics a host cell function required for plant genetic transformation
Published online: 23 December 2004
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