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 Volume 23, Number 3 (11 February 2004)
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About the cover
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| New EMBO Member's Review | top  |
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Take five—BACE and the  -secretase quartet conduct Alzheimer's amyloid  -peptide generation | |
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| Christian Haass | |
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| Articles | top |
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| Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin | |
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| Abarna Thiru, Daniel Nietlispach, Helen R Mott, Mitsuru Okuwaki, Debbie Lyon, Peter R Nielsen, Miriam Hirshberg, Alain Verreault, Natalia V Murzina and Ernest D Laue | |
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| The EMBO Journal (2004) 23, 489–499, doi:10.1038/sj.emboj.7600088
| Abstract | Full text | PDF (504K) | Supplementary Information | Published online: 5 February 2004 | |
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| Subject Categories: Structural Biology | Chromatin & Transcription | |
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| Plasticity in eucaryotic 20S proteasome ring assembly revealed by a subunit deletion in yeast | |
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| Irina Velichutina, Pamela L Connerly, Cassandra S Arendt, Xia Li and Mark Hochstrasser | |
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| The EMBO Journal (2004) 23, 500–510, doi:10.1038/sj.emboj.7600059
| Abstract | Full text | PDF (418K) | Published online: 22 January 2004 | |
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| Subject Categories: Proteins | Structural Biology | |
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| Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery | |
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| Philippe Meyer, Chrisostomos Prodromou, Chunyan Liao, Bin Hu, S Mark Roe, Cara K Vaughan, Ignacija Vlasic, Barry Panaretou, Peter W Piper and Laurence H Pearl | |
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| The EMBO Journal (2004) 23, 511–519, doi:10.1038/sj.emboj.7600060
| Abstract | Full text | PDF (391K) | Published online: 22 January 2004 | |
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| Subject Categories: Proteins | Structural Biology | |
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| Preprotein recognition by the Toc complex | |
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| Thomas Becker, Marko Jelic, Aleksandar Vojta, Alfons Radunz, Jürgen Soll and Enrico Schleiff | |
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| The EMBO Journal (2004) 23, 520–530, doi:10.1038/sj.emboj.7600089
| Abstract | Full text | PDF (467K) | Published online: 5 February 2004 | |
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| Subject Categories: Plant Biology | |
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| Regulated exocytosis of an H+/myo-inositol symporter at synapses and growth cones | |
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| Marc Uldry, Pascal Steiner, Marie-Gabrielle Zurich, Pascal Béguin, Harald Hirling, Wanda Dolci and Bernard Thorens | |
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| The EMBO Journal (2004) 23, 531–540, doi:10.1038/sj.emboj.7600072
| Abstract | Full text | PDF (392K) | Published online: 29 January 2004 | |
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| Subject Categories: Membranes & Transport | Neuroscience | |
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| Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells | |
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| Fumiko Itoh, Susumu Itoh, Marie-José Goumans, Gudrun Valdimarsdottir, Tatsuya Iso, G Paolo Dotto, Yasuo Hamamori, Larry Kedes, Mitsuyasu Kato and Peter ten Dijke | |
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| The EMBO Journal (2004) 23, 541–551, doi:10.1038/sj.emboj.7600065
| Abstract | Full text | PDF (470K) | Published online: 22 January 2004 | |
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| Subject Categories: Chromatin & Transcription | Cell & Tissue Architecture | |
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| Endogenous TGF- signaling suppresses maturation of osteoblastic mesenchymal cells | |
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| Shingo Maeda, Makoto Hayashi, Setsuro Komiya, Takeshi Imamura and Kohei Miyazono | |
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| The EMBO Journal (2004) 23, 552–563, doi:10.1038/sj.emboj.7600067
| Abstract | Full text | PDF (443K) | Supplementary Information | Published online: 29 January 2004 | |
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| Subject Categories: Signal Transduction | Differentiation & Death | |
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| The protein kinase PKR: a molecular clock that sequentially activates survival and death programs | |
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| Olivier Donzé, Jing Deng, Joseph Curran, Robert Sladek, Didier Picard and Nahum Sonenberg | |
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| The EMBO Journal (2004) 23, 564–571, doi:10.1038/sj.emboj.7600078
| Abstract | Full text | PDF (261K) | Supplementary Information | Published online: 29 January 2004 | |
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| Subject Categories: Differentiation & Death | Signal Transduction | |
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| A protein kinase target of a PDK1 signalling pathway is involved in root hair growth in Arabidopsis | |
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| Richard G Anthony, Rossana Henriques, Anne Helfer, Tamás Mészáros, Gabino Rios, Christa Testerink, Teun Munnik, Maria Deák, Csaba Koncz and László Bögre | |
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| The EMBO Journal (2004) 23, 572–581, doi:10.1038/sj.emboj.7600068
| Abstract | Full text | PDF (319K) | Supplementary Information | Published online: 29 January 2004 | |
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| Subject Categories: Signal Transduction | Plant Biology | |
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| Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice | |
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| Gregory J Cooney, Ruth J Lyons, A Jayne Crew, Thomas E Jensen, Juan Carlos Molero, Christopher J Mitchell, Trevor J Biden, Christopher J Ormandy, David E James and Roger J Daly | |
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| The EMBO Journal (2004) 23, 582–593, doi:10.1038/sj.emboj.7600082
| Abstract | Full text | PDF (277K) | Published online: 29 January 2004 | |
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| Subject Categories: Signal Transduction | Molecular Biology of Disease | |
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| The region 3' to Xist mediates X chromosome counting and H3 Lys-4 dimethylation within the Xist gene | |
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| Céline Morey, Pablo Navarro, Emmanuel Debrand, Philip Avner, Claire Rougeulle and Philippe Clerc | |
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| The EMBO Journal (2004) 23, 594–604, doi:10.1038/sj.emboj.7600071
| Abstract | Full text | PDF (330K) | Supplementary Information | Published online: 29 January 2004 | |
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| Subject Categories: Chromatin & Transcription | RNA | |
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| A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells | |
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| Slimane Ait-Si-Ali, Valentina Guasconi, Lauriane Fritsch, Hakima Yahi, Redha Sekhri, Irina Naguibneva, Philippe Robin, Florence Cabon, Anna Polesskaya and Annick Harel-Bellan | |
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| The EMBO Journal (2004) 23, 605–615, doi:10.1038/sj.emboj.7600074
| Abstract | Full text | PDF (260K) | Published online: 5 February 2004 | |
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| Subject Categories: Chromatin & Transcription | Cell Cycle | |
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| Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase | |
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| Isabelle Kaufmann, Georges Martin, Arno Friedlein, Hanno Langen and Walter Keller | |
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| The EMBO Journal (2004) 23, 616–626, doi:10.1038/sj.emboj.7600070
| Abstract | Full text | PDF (580K) | Supplementary Information | Published online: 29 January 2004 | |
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| Subject Categories: RNA | |
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| Differential functional interplay of TOGp/XMAP215 and the KinI kinesin MCAK during interphase and mitosis | |
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| Per Holmfeldt, Sonja Stenmark and Martin Gullberg | |
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| The EMBO Journal (2004) 23, 627–637, doi:10.1038/sj.emboj.7600076
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| Hsp42 is the general small heat shock protein in the cytosol of Saccharomyces cerevisiae | |
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| Martin Haslbeck, Nathalie Braun, Thusnelda Stromer, Bettina Richter, Natascha Model, Sevil Weinkauf and Johannes Buchner | |
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| The EMBO Journal (2004) 23, 638–649, doi:10.1038/sj.emboj.7600080
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| Subject Categories: Proteins | |
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| A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised | |
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| Daniël Blom, Christian Hirsch, Patrick Stern, Domenico Tortorella and Hidde L Ploegh | |
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| The EMBO Journal (2004) 23, 650–658, doi:10.1038/sj.emboj.7600090
| Abstract | Full text | PDF (276K) | Published online: 29 January 2004 | |
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| Subject Categories: Proteins | Microbiology & Pathogens | |
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| Molecular clearance of ataxin-3 is regulated by a mammalian E4 | |
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| Masaki Matsumoto, Masayoshi Yada, Shigetsugu Hatakeyama, Hiroshi Ishimoto, Teiichi Tanimura, Shoji Tsuji, Akira Kakizuka, Masatoshi Kitagawa and Keiichi I Nakayama | |
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| The EMBO Journal (2004) 23, 659–669, doi:10.1038/sj.emboj.7600081
| Abstract | Full text | PDF (425K) | Published online: 29 January 2004 | |
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| Subject Categories: Proteins | Molecular Biology of Disease | |
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| XRCC3 deficiency results in a defect in recombination and increased endoreduplication in human cells | |
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| Takashi Yoshihara, Mari Ishida, Aiko Kinomura, Mari Katsura, Takanori Tsuruga, Satoshi Tashiro, Toshimasa Asahara and Kiyoshi Miyagawa | |
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| The EMBO Journal (2004) 23, 670–680, doi:10.1038/sj.emboj.7600087
| Abstract | Full text | PDF (255K) | Published online: 29 January 2004 | |
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| Subject Categories: Genome Stability & Dynamics | |
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